Publications by authors named "Aya Matsuno"
Article Synopsis
- Researchers aimed to improve a probe ([Ga]CG6) used for detecting pancreatic cancer by reducing its accumulation in non-target organs like the liver and spleen, which may have been caused by its positive charge.
- A new probe ([Ga]CD6) was synthesized with a different electric charge, showing similar binding affinity to pancreatic cancer cells but significantly less uptake in the liver and spleen compared to the original probe.
- The study concluded that the modified probe ([Ga]CD6) is more effective for targeting pancreatic ductal adenocarcinoma (PDAC) while minimizing unwanted side effects in surrounding organs.
A maltose binding protein, p78, was purified to homogeneity from Aspergillus nidulans by a single column chromatography step on cross-linked amylose. The partial amino acid sequence was highly homologous to the glycogen branching enzymes (GBEs) of human and yeast, and p78 did show branching enzyme activity. The genomic gene and its cDNA encoding GBE (p78) were isolated from the A.
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