Correction: Motivators and barriers to research participation among medical students in Saudi Arabia.

[This corrects the article DOI: 10.1371/journal.pone.

Effect of interleukin 6 (IL-6) on sperm quality, kinematic parameters, acrosome integrity, apoptosis, ultrastructure, and molecular docking in cryopreserved ram spermatozoa.

Sperm cryopreservation can lead to subfertility due to potential damage to sperm DNA, membranes, and overall motility caused by the freeze-thaw process. Interleukin-6 (IL-6) is a versatile cytokine with various roles in reproductive processes. However, the impacts of IL-6 supplementation on cryopreserved ram sperm have not been thoroughly investigated.

Alzheimer Disease Associated Loci: Single Nucleotide Polymorphisms in Marmara Region.

Alzheimer's disease (AD) is a major global health challenge, especially among individuals aged 65 or older. According to population health studies, Turkey has the highest AD prevalence in the Middle East and Europe. To accurately determine the frequencies of common and rare single nucleotide polymorphisms (SNPs) in the Turkish population residing in the Marmara Region, we conducted a retrospective study analyzing variants in 588 individuals referred to the Bursa Uludag University Genetic Diseases Evaluation Center.

Gene Variation's Impact on Cardiovascular Health: A Case-Control Study.

Chronic venous insufficiency (CVI) is a common medical condition characterized by impaired functioning of the venous system in the lower extremities. It leads to various symptoms, including varicose veins, leg edema, and skin pigmentation. It is believed that a combination of genetic and environmental factors affect the development of CVI.

Frailty and Pre-Frailty in the Setting of Total Joint Arthroplasty: A Narrative Review.

Background: Total joint arthroplasties are among the most common surgical procedures performed in the United States. Although numerous safeguards are in place to optimize patient health and safety pre-, intra-, and postoperatively, patient frailty is often incompletely assessed or not assessed at all. Frailty has been shown to increase rates of adverse events and length of stay.

Mediterranean exposotype: Genomic architecture and plant-based dietary metabolites.

The most well-grounded dietary pattern involved in nutrigenenic studies investigating non -communicable diseases is the Mediterranean diet. This dietary regime is inspired by the nutritional habits of people residing near Mediterranean Sea. The fundamental elements of this diet can vary based on ethnicity, culture, economic status and religious properties and are associated with lowercases of all-cause mortality rates.

Motivators and barriers to research participation among medical students in Saudi Arabia.

Little is known about the obstacles medical students face when conducting research in Saudi Arabia. Moreover, the proportion of medical students in research has been unknown in our region compared to other regions. We sought to identify the barriers and motivators that influence undergraduate medical students in pursuing research.

The expression profile of WNT/β-catanin signalling genes in human oocytes obtained from polycystic ovarian syndrome (PCOS) patients.

Polycystic ovarian syndrome (PCOS) is a chronic hormonal turmoil that is demonstrated in 2.2-27% of women of pre-menopausal age. This disease is a complex multigenic disorder that results from the interaction between excess androgen expression, genetic susceptibility and environmental influences.

Current Guidelines and Practice Recommendations to Prevent Hospital-Acquired Conditions After Major Orthopaedic Surgeries.

»: In 2016, a total of 48,771 hospital-acquired conditions (HACs) were reported in U.S. hospitals.

Deepfake video detection: YOLO-Face convolution recurrent approach.

Recently, the deepfake techniques for swapping faces have been spreading, allowing easy creation of hyper-realistic fake videos. Detecting the authenticity of a video has become increasingly critical because of the potential negative impact on the world. Here, a new project is introduced; You Only Look Once Convolution Recurrent Neural Networks (YOLO-CRNNs), to detect deepfake videos.

A New Deep Learning-Based Methodology for Video Deepfake Detection Using XGBoost.

Currently, face-swapping deepfake techniques are widely spread, generating a significant number of highly realistic fake videos that threaten the privacy of people and countries. Due to their devastating impacts on the world, distinguishing between real and deepfake videos has become a fundamental issue. This paper presents a new deepfake detection method: you only look once-convolutional neural network-extreme gradient boosting (YOLO-CNN-XGBoost).

Hospital-Acquired Conditions: A Review of Classical and Novel Risk Factors Following Total Hip and Knee Arthroplasties.

»: In 2016, a total of 48,771 hospital-acquired conditions (HACs) were reported in U.S. hospitals.

Free-B-Ring flavonoids as potential lead compounds for colon cancer therapy.

Although flavonoids have been identified as a versatile source of anticancer agents, to the best of our knowledge, no study has yet investigated their anticolon cancer activity in depth. Therefore, the aim of this study was to investigate the association between the structural characteristics of flavonoids and their anticolon cancer activity in the Caco-2 human colon cancer cell line. Our findings demonstrated that the hydroxylation of C5 and C7 in ring A significantly enhanced the anticolon cancer activity of flavonoids over that of 5-fluorouracil, the classic reference cytotoxic agent.