Economic Evaluation of Total Knee Replacement Compared with Non-Surgical Management for Knee Osteoarthritis in India.

Objective: This study is an economic evaluation of total knee replacement (TKR) in comparison with non-surgical management in India.

Methods: Cost-utility analysis and budget impact analysis (BIA) were conducted on individuals aged ≥ 50 years with osteoarthritis of the knee (OA knee) Kellgren-Lawrence grades 2 and 3 using a provider's perspective. Three scenarios were considered, varying the age at which TKR is administered while assuming a 20-year lifespan for the implant.

The Effect of Spinal Needle Type on Post-Dural Puncture Headache in Spinal Anesthesia: Prospective Randomized Study.

Background:  Postdural puncture headache is a headache that occurs after a dura puncture, especially in caesarean sections, and afects patient comfort and mobilization. In this study, we compared the efects of pencil-tipped spinal needles and especially curved, bilateral atraumatic spinal needles in individuals undergoing elective caesarean sections.

Methods:  A total of 886 patients, aged 20-50 years, who had cesarean sections with spinal anesthesia and had American Society of Anesthesiologists II and III scores, were included in the study.

Outsourcing Control Requires Control Complexity.

An embodied agent influences its environment and is influenced by it. We use the sensorimotor loop to model these interactions and quantify the information flows in the system by information-theoretic measures. This includes a measure for the interaction among the agent's body and its environment, often referred to as morphological computation.

Lymphocele Outcomes After Renal Transplantations Performed by an Experienced Surgeon: Is Meticulously Performed Surgery and Experience Adequate to Prevent Lymphocele?

BACKGROUND The purpose of the present study was to analyze the rate of lymphoceles in kidney transplant operations meticulously performed by the same senior surgeon. MATERIAL AND METHODS The present study included 315 patients who were operated on in our organ transplantation center and followed up in the polyclinic after July 2013. The patients were retrospectively divided into 2 groups: patients with and without lymphocele.

Electrochemical DNA biosensors developed for the monitoring of biointeractions with drugs: a review.

The interaction of drugs with DNA is important for the discovery of novel drug molecules and for understanding the therapeutic effects of drugs as well as the monitoring of side effects. For this reason, many studies have been carried out to investigate the interactions of drugs with nucleic acids. In recent years, a large number of studies have been performed to electrochemically detect drug-DNA interactions.

Real-life outcomes of COVID-19 vaccination in kidney transplant patients: a single-center experience.

Introduction: In this study, it was aimed to investigate the clinical (real-life) impact of the vaccination protocol on patients undergoing kidney transplantation during the COVID-19 pandemic.

Methodology: A total of 260 patients who underwent kidney transplantation between June 2012 and May 2022 were retrospectively evaluated. Patients chose vaccination Sinovac-CoronaVac (CoronaVac) and/or BNT162b2 (Biontech), the first vaccine available in the country) in line with the regulations and recommendations of the Ministry of Health.

Boron Nitride's Morphological Role in the Design of Injectable Hyaluronic Acid Based Hybrid Artificial Synovial Fluid.

The treatment process of osteoarthritis (OA) is challenging as it affects not only cartilage but also subchondral bone, ligament attachment capsules, synovium, and surrounding muscle tissue. Therefore, the search for preventive treatment or methods to slow the onset of the condition. Hexagonal boron nitride (hBN) has a graphite-like lamellar structure and is thought to facilitate cartilage movement for biomedical applications, just like in bearing systems.

Potential use of (V. Tiegh.) Lec. extract for the treatment of diabetes.

Introduction: Balanophora latisepala (BL) is a chlorophyll-free and obligate parasitic plant found across mountainous areas of An Giang, Vietnam. This study was conducted to evaluate the effectiveness of extracts from BL, herbs mentioned in many traditional medicines in the treatment of diabetes, on laboratory mice.

Materials And Methods: The effects of BL aqueous, methanol, and ethanol extracts on the blood glucose levels, hematological indices, liver enzymes, and pancreatic tissue structure of normal, glucose-tolerant mice, and diabetic mice treated with streptozotocin (STZ) were assessed.

The biomechanical stability of miniplate osteosynthesis configurations in bilateral mandibular angle fractures.

Purpose: The present study investigated the biomechanical stability of three miniplate osteosynthesis configurations used for internal fixation of bilateral mandibular angle fracture (BMAF).

Methods: Standard fracture lines were created in 72 polyurethane mandibles and stabilized with 2.0-mm, 4-hole standard titanium miniplates and monocortical screws.

The mediating role of self-compassion in the relationship between internalized stigma and psychological resilience in bipolar disorder.

Introduction: Internalized stigma is known to be high in bipolar disorder (BD). Concepts such as self-compassion and psychological resilience have recently begun to be studied as protective factors for BD. The aim of the current study was to examine the relationships between internalized stigma, self-compassion and resilience among individuals with BD.

Isolation and purification of potential weed inhibitors from L.

The diversity in structure and herbicidal properties detected in natural phytotoxic compounds could bring about advantages for development bio-herbicides. The present study was carried out search for potential weed inhibitors from the parts of L. The ethyl acetate (EtOAc) extract of leaf of showed inhibitory activity during the time that (barnyardgrass) germinates and grows, which is greater than that of other extracts.

Can a novel drug dose be used for T3 suppression test?

Purpose: This study aimed to investigate whether 25 µg/day dose of triiodothyronine (T3) can also suppress thyroid stimulating hormone (TSH) level, as well as the routine dose of 50-100 µg/day in T3 suppression test, which is used to the distinguish between resistance to thyroid hormone (RTH) and TSH secreting pituitary adenoma.

Methods: In this prospective study, 26 patients with genetically proven RTH were randomly divided into two groups: Group 1 comprised 13 patients who were administered 50-100 µg/day T3 for 3-9 days, while Group 2 also comprised 13 patients who were administered 25 µg/day T3 for 7 days for T3 suppression test. The two groups' responses to T3 suppression tests were compared.

Predictive value of CHA2DS2-VASc score in radial artery occlusion after transradial coronary angiography.

Background: Radial artery occlusion is the most common complication of transradial catheterization. RAO is characterized by thrombus formation due to catheterization and endothelial damage. CHA2DS2-VASc scores are the current scoring systems used to determine the risk of thromboembolism in patients with atrial fibrillation.

Predictive Ability of Serum Uric Acid Levels in Assessing the Severity of Chronic Liver Disease.

Introduction: Study aims to assess uric acid levels with severity of CLD, which is in turn a marker of inflammation and to establish cut off levels with severity of CLD in the current study.

Materials: This is a cross-sectional study conducted among 100 subjects aged ≥18 years, with chronic liver disease for a period of 1 year. The data was collected, serum uric acid levels were determined and the severity of CLD was assessed using Child Turcotte Pugh (CTP) scoring.

Variables affecting mortality rates in patients undergoing emergency abdominal surgery: A retrospective cross-sectional study.

Background: Patients operated under emergency conditions have a higher risk of death and complications than those per-formed under elective conditions. Especially the patient group with high comorbidity needs to be evaluated more specifically. Accord-ing to the surgical risk and American Society of Anesthesiologists (ASA) scoring, the perioperative risk should be determined quickly, and the relatives of the patients should be informed.

Evaluation of immunomodulatory nutrients in critically ill patients in the intensive care unit.

Objective: Glutamine and omega-3 fatty acids have been shown to decrease infection rates, antibiotic use, and hospital length of stay. However, whether giving immunonutrients to critically ill patients is beneficial remains controversial. In our study, we aimed to look at the effectiveness of parenteral unsaturated (omega-3) fatty acids and amino acid glutamine in patients with serious conditions in the intensive care unit (ICU).

Natural Reweighted Wake-Sleep.

Helmholtz Machines (HMs) are a class of generative models composed of two Sigmoid Belief Networks (SBNs), acting respectively as an encoder and a decoder. These models are commonly trained using a two-step optimization algorithm called Wake-Sleep (WS) and more recently by improved versions, such as Reweighted Wake-Sleep (RWS) and Bidirectional Helmholtz Machines (BiHM). The locality of the connections in an SBN induces sparsity in the Fisher Information Matrices associated to the probabilistic models, in the form of a finely-grained block-diagonal structure.

Analysis of COVID-19 infection in hemodialysis and kidney transplant patients in a pandemic hospital.

Introduction: The mortality rate for any infection is often higher in patients with a kidney transplant (KT) and hemodialysis (HD), which may also be the case in novel coronavirus disease 2019 (COVID-19).

Methodology: In this study, the demographic, clinic, laboratory, and radiologic signs of KT and HD patients diagnosed with COVID-19 infection between 11th March 2020 and 11th March 2021 were evaluated prospectively.

Results: In the present study, 72 HD (median age, 57.

The Importance of Anatomic Configuration and Cystic Changes in Macular Hole: Predicting Surgical Success with a Different Approach.

Purpose: This study aimed to define a novel metric for the area of the macular hole (MH) and cysts located around the hole using an optical coherence tomography (OCT) device.

Methods: This study was conducted with 58 eyes of 56 patients. The patients were divided into two groups according to anatomic closure after surgery.

Serum Elabela level is significantly increased in patients with acromegaly.

Background: Although the bioactive peptides associated with the apelinergic system are known to be associated with heart failure and ischemic heart disease, there are no data on their association with acromegaly.

Aim: We aimed to investigate the change in serum Elabela levels, a novel peptide of the apelinergic system, in patients with acromegaly.

Methods: Our study included 30 treatment naive patients who were recently diagnosed with acromegaly, and 50 age-and-sex-matched healthy controls.

The insecticidal capacity of ethanol extract from (L.) Lippold against fruit fly.

(L.) Lippold () has been extensively used for its antifungal and antibacterial properties. However, its role in anti-insect is still under investigation.

Identification of Pathogens Causing Anthracnose on King Oranges ( var. Typica Hassk).

<b>Background and Objective:</b> Anthracnose is one of the main causes seriously affecting the fruit yield and quality of king oranges. This study aimed to identify the fungal pathogen <i>Colletotrichum gloeosporioides</i> causing anthracnose on king oranges in Vinh Long. <b>Materials and Methods:</b> Fruits with diseases were collected from the king orange garden located in Vinh Long in September, 2020.

Ipsilateral Vestibular Schwannoma after Cochlear Implantation.

Objective: The vestibular schwannoma incidence rate is approximately 4.2 per 100,000/year. Thus far, about 700,000 cochlear implantations have been performed worldwide; therefore, the occurrence of vestibular schwannoma postcochlear implantations can be assumed to be infrequent.

How Morphological Computation Shapes Integrated Information in Embodied Agents.

The Integrated Information Theory provides a quantitative approach to consciousness and can be applied to neural networks. An embodied agent controlled by such a network influences and is being influenced by its environment. This involves, on the one hand, morphological computation within goal directed action and, on the other hand, integrated information within the controller, the agent's brain.

Nasopharyngeal Coil Dislocation of an Embolized Internal Carotid Artery Pseudoaneurysm.

Objective: Severe epistaxis caused by ruptured intracranial pseudoaneurysms can be effectively treated by coil embolization. This is generally an efficient and safe procedure and provides sufficient protection recurrent epistaxis. However, complications such as aneurysm rupture, arterial dissection, bleeding, and emboli can occur.