Publications by authors named "Axel Rodriguez"
Article Synopsis
- Screenwide is a case-control study conducted in Spain from 2017 to 2021 that looked at women with endometrial and ovarian cancers, along with BRCA1/2 and MMR pathogenic variant carriers, to identify risk factors and molecular biomarkers for these cancers.
- Participants provided detailed personal and medical information, along with biological samples like blood and self-collected vaginal specimens, to facilitate comprehensive analyses.
- Preliminary findings from a pilot study indicate that certain genetic variants associated with tumors can be effectively detected in less invasive samples, suggesting potential for improved early detection strategies for gynecological cancers.
Zirconium phosphate (ZrP) nanoplatelets can intercalate anticancer agents via an ion exchange reaction creating an inorganic delivery system with potential for cancer treatment. ZrP delivery of anticancer agents inside tumor cells was explored in vitro. Internalization and cytotoxicity of ZrP nanoplatelets were studied in MCF-7 and MCF-10A cells.
View Article and Find Full Text PDFHuman epidermal growth factor receptor (HER1) constitutes a tumor associated antigen. Its overexpression in many epithelial tumors has been associated with bad prognosis and poor survival. Cancer vaccine based on the extracellular domain (ECD) of HER1 and adjuvated in very small sized proteoliposomes (VSSP) and Montanide ISA 51-VG is a new and complementary approach for the treatment of epithelial tumors.
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