Mini- and micro-screws for temporary skeletal anchorage in orthodontic therapy.

Objective: Mini- and micro-screws are of increasing interest in orthodontic therapy in cases where maximum anchorage is requested. In this study we aimed to identify the criteria that influence the clinical success of micro-implants.

Material And Methods: 239 micro-implants were inserted for skeletal anchorage in 85 patients undergoing orthodontic therapy.

Proliferative (MIB1, mdm2) Versus Anti-Proliferative (p53) Markers in Head and Neck Cancer. An Immunohistochemical Study.

Formalin fixed and paraffin embedded samples from 36 squamous cell carcinomas of the larynx and the oral cavity (pT2N0M0, R0) surrounded by non-tumorous mucosa were studied immunohistochemically using a panel of four different anti-p53 antibodies (CM1, PAb1801, D07, PAb240), a monoclonal anti-mdm2 antibody and MIB1, following wet autoclave antigen retrieval. P53 immunoreactivity was detected in 11/14 laryngeal and in 9/22 oral carcinomas. All p53 positive oral, and all but one laryngeal tumors revealed mdm2 positivity as well, whereas in p53 negative tumors 4/12 and 1/3 mdm2 immunopositive cases were demonstrated, respectively.