Comparison of high and low dose of cyclophosphamide in lupus nephritis patients: a long-term randomized controlled trial.

To evaluate the outcome of low doses of cyclophosphamide (Cyclo) therapy in lupus nephritis (LN) patients, we studied 117 biopsy-proven, de novo LN WHO class IV patients double-blinded and randomized in December 1997 to receive Cyclo in different doses; Group I (n=73) received Cyclo 10 mg/kg monthly for six months then every two months for 12 months. Group II (n=44) received Cyclo 5 mg/kg monthly for six months then every two months for 36 months. The patients were followed-up till January 2007.

A validation study comparing the sensitivity and specificity of the new Dr. KSU H1N1 RT-PCR kit with real-time RT-PCR for diagnosing influenza A (H1N1).

Background And Objectives: A new test (Dr. KSU H1N1 RT-PCR kit) was recently developed to provide a less expensive alternative to real-time reverse transcriptase-polymerase chain reaction (RT-PCR). We report the findings of a validation study designed to assess the diagnostic accuracy, including sensitivity and specificity, of the new kit, as compared to real-time RT-PCR.

Dyslipidemia in dialysis patients.

In order to evaluate the lipid profiles of dialysis patients, we retrospectively reviewed all the chronic kidney disease (CKD) patients on chronic hemodialysis (HD) or continuous ambulatory peritoneal dialysis (CAPD), followed up between June 2004 and May 2005, in two tertiary hospitals in Riyadh, Saudi Arabia. There were 380 patients including 206 (54.2%) females and the mean age of the patients was 45.

How do medical students in their clinical years perceive basic sciences courses at King Saud University?

Background And Objectives: The inclusion of detailed basic science courses in medical school curricula has been a concern of students. The main objective of this study was to explore the attitudes of medical students towards basic sciences courses taught to them in the preclinical years and the applicability of these courses to current clinical practice.

Design And Setting: A cross-sectional survey was conducted during 2008-2009 among medical students in their clinical years at King Saud University, Riyadh, Saudi Arabia.

Concomitant macro and microvascular complications in diabetic nephropathy.

To determine the prevalence of concomitant microvascular and macrovascular complications of diabetic nephropathy we retrospectively reviewed the medical records of all 1,952 type 2 diabetic patients followed-up at Security Forces Hospital, Riyadh, Saudi Arabia from January 1989 to December 2004. There were 626 (32.1%) patients (294 (47%) were males) who developed diabetic nephropathy.

Obesity among female school children in North West Riyadh in relation to affluent lifestyle.

Objective: To estimate the prevalence of obesity among elementary school female students and to identify some obesity-associated risk factors.

Methods: This cross-sectional study surveyed healthy female school students (grades 4-6) during 2006-2007. Four private schools in North West Riyadh, Kingdom of Saudi Arabia were selected where the majority of high income families enrolled their daughters.

Diabetes complications in 1952 type 2 diabetes mellitus patients managed in a single institution in Saudi Arabia.

Background And Objectives: Because there is no recent update on the state of diabetes and its concomitant complications in Saudi Arabia, we undertook a study of the prevalence of health complications in patients with type 2 diabetes mellitus admitted to our institution.

Methods: We conducted a retrospective review of medical records of adult Saudi patients with type 2 diabetes who were seen in clinics or admitted to the Security Forces Hospital, Riyadh, Saudi Arabia, between January 1989 and January 2004.

Results: Of 1952 patients, 943 (48.

Complications of CAPD: A Single Center Experience.

To evaluate the complications of CAPD and their contributing factors in order to improve the patients' survival and reduce morbidity and mortality, we studied records of 65 CAPD patients treated at our hospital from October 1996 to January 2002. There were 32 (49%) males and the mean age of the patients was 48 +/- 16 years. All the patients were on the twin bag CAPD system.

L-carnitine supplementation in hemodialysis patients.

L-Carnitine supplementation has shown beneficial effects in patients on hemodialysis. We studied 36 ESRD adult patients with a mean age of 47.5 +/- 15 years to evaluate the effect of L-Carnitine supplementation on hemoglobin, lipid levels and physical performance in patients on hemodialysis.

Spectrum and outcome of primary glomerulonephritis.

Glomerulonephritis (GN) is a major cause of chronic renal failure (CRF). To evaluate the trends and outcome with modern improved treatment strategies, we retrospectively reviewed the clinical records of 120 patients with biopsy proven primary GN at our center from January 1990 to June 2001. All the biopsy specimens were subjected to light, electron and immunofluorescent microscopy.

Public opinion on organ donation in Saudi Arabia.

To evaluate factors affecting the knowledge and/or attitudes of the Saudi Arabian public with respect to organ donation and transplantation, a cross sectional study was conducted on a random sample of 948 Saudi citizens between 20-60 years of age during 2005. The collected data included: knowledge about organ donation campaigns, knowledge of the Saudi Center for Organ Transplantation (SCOT), religious knowledge towards related issues, attitudes toward organ donation and self or close-relative experience of organ transplantation. The study revealed that 58.

Knowledge of breast cancer and its risk and protective factors among women in Riyadh.

Background: We conducted this study to assess knowledge of breast cancer and sources of information about breast cancer among women in Riyadh. We also analyzed whether associations existed between demographic variables, knowledge of breast cancer, and the practice of breast self-examination and use of mammography screening.

Methods: Women interested in participating in this community-based descriptive study provided data by completing a pre-tested structured

Results: Of 864 participating women, 84% were Saudi, 45% were married and 67.

Perception of female students of king saud university towards premarital screening.

Objectives: The aim of this study was to investigate the perception of King Saud University female students towards the implementation of premarital screening (PMS) in the Kingdom of Saudi Arabia (KSA).

Methods: Two consecutive surveys on knowledge, attitudes and practice (KAP) were conducted two and nine months after the compulsory implementation of PMS in KSA in 1/1/1425H. The female students of King Saud University were given health education lectures before the survey.

Effect of chronic viral hepatitis on graft survival in Saudi renal transplant patients.

Background: In Saudi Arabia the prevalence of hepatitis C among hemodialysis patients is very high ranging from 60 to 80%. A large number of these dialysis patients go for renal transplant, resulting into a higher prevalence of hepatitis C virus (HCV) infection in renal transplant patients. Yet no current systematic report is available on the influence of hepatitis C status on patient and graft survival.

Plasma fibrinogen and its correlates in adult Saudi population.

Objective: To determine plasma fibrinogen and its correlates in the adult Saudi population and to investigate hyperfibrinogenemia as a possible risk factor for cardiovascular diseases (CVD).

Methods: A cross-sectional survey was designed and carried out through multi-stage stratified cluster random sampling of every third house in 6 heterogeneously populated districts of Riyadh, Kingdom of Saudi Arabia, during the period 1999 to 2002. Demographic and clinical data of 2263 adult Saudi subjects, consisting of 1934 (85.