Combating the causative agent of amoebic keratitis, Acanthamoeba castellanii, using Padina pavonica alcoholic extract: toxicokinetic and molecular docking approaches.

Natural products play a significant role in providing the current demand as antiparasitic agents, which offer an attractive approach for the discovery of novel drugs. The present study aimed to evaluate in vitro the potential impact of seaweed Padina pavonica (P. pavonica) extract in combating Acanthamoeba castellanii (A.

Enhancement of phycocyanin productivity and thermostability from Arthrospira platensis using organic acids.

Intracellular hyperaccumulation of phycocyanin (PC) and its high susceptibility to degradation at higher temperatures are major challenging problems associated with its production from cyanobacteria. The present study evaluated different concentrations of organic acids (1, 2, and 3 mM) (citric acid, acetic acid, succinic acid, fumaric acid, and oxalic acid) under fed-batch mode on the biomass and phycobiliproteins' production from Arthrospira platensis. Besides they were evaluated at 2.

Low-cost biosorption of Fe(II) and Fe(III) from single and binary solutions using Ulva lactuca-derived cellulose nanocrystals-graphene oxide composite film.

The marine algal biomass of Ulva lactuca was utilized for the extraction of cellulose and the development of cellulose nanocrystals/graphene oxide film. Cellulose nanocrystals with 50-150 nm were produced by HSO hydrolysis of the algal cellulose. The adsorption efficiency of the nanocomposite film for Fe(II) and Fe(III) ions was successfully evaluated using Box-Behnken design.

Hormesis effects of phenol on growth and cellular metabolites of Chlorella sp. under different nutritional conditions using response surface methodology.

The present study investigated the effects of different phenol concentrations (200 - 1000 mg L) towards Chlorella sp. under different culture conditions (light vs. dark) and NaNO concentrations (0 - 0.

Fungicidal activities and molecular docking of the marine alga Ulva lactuca and Punica granatum peel extracts on Alternaria tomato spot disease.

In this study, we utilized pomegranate peel and marine algae Ulva lactuca (U. lactuca) as rich and sustained sources of bioactive compounds to combat tomato-black spot disease. n-Hexane extracts from the peel of pomegranate (Punica granatum) (PPE) and the marine algal biomass U.

Biosorption of ketoprofen and diclofenac by living cells of the green microalgae Chlorella sp.

There is a growing interest for the removal of different pharmaceuticals from water owing to their toxicity to various organisms. The present study investigated the use of living cells of the green alga Chlorella sp. in the short-term adsorption of ketoprofen (KET) and diclofenac (DIF) from aqueous solutions.

Environmental risk analysis of pharmaceuticals on freshwater phytoplankton assemblage: effects on alpha, beta, and taxonomic diversity.

Antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs) have a wide range of bioactivities and are released into the ecosystem in large amounts. Heretofore, little information is available regarding their potential risk to the phytoplankton assemblage. Different alpha, taxonomic, and beta diversity measures were investigated and linked to the spatial variation of nine drugs.

Upgrading the antioxidant properties of fucoidan and alginate from Cystoseira trinodis by fungal fermentation or enzymatic pretreatment of the seaweed biomass.

The seaweed Cystoseira trinodis was fermented by different fungi prior to extraction of fucoidan and alginate to enhance their antioxidative potential. All the investigated fungi were able to produce fucoidanase (1.05-3.

Statistical Optimization of Culture Variables for Enhancing Agarase Production by Dendryphiella arenaria Utilizing Palisada perforata (Rhodophyta) and Enzymatic Saccharification of the Macroalgal Biomass.

Agarase is a promising biocatalyst for several industrial applications. Agarase production was evaluated by the marine fungus Dendryphiella arenaria utilizing Palisada perforata as a basal substrate in semi-solid state fermentation. Seaweed biomass, glucose, and sucrose were the most significant parameters affecting agarase production, and their levels were further optimized using Box-Behnken design.

Optimization of alginate alkaline extraction technology from Sargassum latifolium and its potential antioxidant and emulsifying properties.

Alginate was recovered from Sargassum latifolium biomass using different conditions of alkali treatment. Box-Behnken experimental design was evaluated to study the influence of alkali:alga ratio, temperature and time on alginate yield, and its molecular weight (MW) and mannuronic/guluronic acid ratio (M/G). The second-order polynomial equations were analyzed by appropriate statistical methods.

Adaptation to iron deficiency: a comparison between the cyanobacterium Synechococcus elongatus PCC 7942 wild-type and a DpsA-free mutant.

To learn more about the adaptive response of Synechococcus elongatus PCC 7942 to iron starvation and the role of DpsA, presumably a protein protecting chromosomal DNA against oxidative damage, we performed a comparative analysis of S. elongatus PCC 7942 wild-type and a DpsA-free mutant, called K11. Relative to wild-type, the DpsA-free mutant had significantly higher amounts of phycocyanin and allophycocyanin, even upon iron limitation.