Large area multi-filamentary plasma source for large volume plasma device-upgrade.

This paper discusses the salient features and plasma performance of the newly installed Large Area Multi-Filamentary Plasma Source (LAMPS) in large volume plasma device-upgrade. The plasma source is designed to exhibit a plasma electron density of ∼10 m, low electron temperature (∼eV), and a uniform plasma cross section of 2.54 m.

Wearable and implantable devices for drug delivery: Applications and challenges.

Poor adherence to drug dosing schedule is responsible for ∼50% of hospitalization cases. Most patients fail to adhere to a strict dosing schedule due to invasive drug administration, off-target toxicities, or medical conditions like dementia. The emerging concept of wearable devices (WDs), implantable devices (IDs) and combined wearable and implantable devices (WIDs) for drug delivery has created new opportunities for treating patients with chronic diseases needing repeated and long-term medical attention like diabetes, ocular disorders, cancer, wound healing, cardiovascular diseases, and contraception.

Phospholipid and menthol based nanovesicle impregnated transdermal patch for nutraceutical delivery to diminish folate and iron deficiency.

Adequate micronutrient availability is particularly important in women, children and infants. Micronutrient deficiencies are the major cause of maternal and neonatal morbidity. To overcome this, WHO recommends the use of folic acid and iron supplements for reducing anaemia and improving the health of the mother and infants.

Development of electronic record-keeping software for remote participation in Large Volume Plasma Device upgrade using Angular 2 and NodeJS web technologies.

In an era of digital transformation and collaborations, the Web Information System (WIS) becomes an essential requirement for the information and data sharing of large experimental facilities among users. With the enhancement in the capabilities and performance of web technologies, sharing of experimental data using a flexible, modular, secure, and robust mechanism is feasible. In this direction, the Large Volume Plasma Device (LVPD), an experimental device dedicated for carrying out investigations for unfolding physical phenomena of relevance to Earth's magnetosphere and fusion plasmas, also adopts web-based electronic record keeping for its operation.

Electro-mechanical probe positioning system for large volume plasma device.

An automated electro-mechanical system for the positioning of plasma diagnostics has been designed and implemented in a Large Volume Plasma Device (LVPD). The system consists of 12 electro-mechanical assemblies, which are orchestrated using the Modbus communication protocol on 4-wire RS485 communications to meet the experimental requirements. Each assembly has a lead screw-based mechanical structure, Wilson feed-through-based vacuum interface, bipolar stepper motor, micro-controller-based stepper drive, and optical encoder for online positioning correction of probes.

A 5 kA pulsed power supply for inductive and plasma loads in large volume plasma device.

This paper describes 5 kA, 12 ms pulsed power supply for inductive load of Electron Energy Filter (EEF) in large volume plasma device. The power supply is based upon the principle of rapid sourcing of energy from the capacitor bank (2.8 F/200 V) by using a static switch, comprising of ten Insulated Gate Bipolar Transistors (IGBTs).

Performance of large electron energy filter in large volume plasma device.

This paper describes an in-house designed large Electron Energy Filter (EEF) utilized in the Large Volume Plasma Device (LVPD) [S. K. Mattoo, V.

Revisiting plasma hysteresis with an electronically compensated Langmuir probe.

The measurement of electron temperature in plasma by Langmuir probes, using ramped bias voltage, is seriously affected by the capacitive current of capacitance of the cable between the probe tip and data acquisition system. In earlier works a dummy cable was used to balance the capacitive currents. Under these conditions, the measured capacitive current was kept less than a few mA.

Experimental observation of electron-temperature-gradient turbulence in a laboratory plasma.

We report the observation of electron-temperature-gradient (ETG) driven turbulence in the laboratory plasma of a large volume plasma device. The removal of unutilized primary ionizing and nonthermal electrons from uniform density plasma and the imposition and control of the gradient in the electron temperature (T[Symbol: see text] T(e)) are all achieved by placing a large (2 m diameter) magnetic electron energy filter in the middle of the device. In the dressed plasma, the observed ETG turbulence in the lower hybrid range of frequencies ν = (1-80 kHz) is characterized by a broadband with a power law.

Molecular modeling study of interaction of anthracenedione class of drug mitoxantrone and its analogs with DNA tetrameric sequences.

Numbers of drugs are being synthesized every year to meet the target of safe and disease-free society. Presently molecular modeling technique is used to unfold the mechanism of action of drugs alone or in conjunction with experimental methodologies. There are a number of drugs which are successfully developed using this methodology.

Effect of root extract from Boerhaavia diffusa L., containing an antiviral principle upon plaque formation of RNA bacteriophages.

An extract obtained from the roots of Boerhaavia diffusa plants, which inhibits the infection of several plant viruses, was tested by the agar diffusion hole method for its action on RNA-containing bacterial viruses. Plaque formation of the phages was only partially and non-uniformly influenced by the extract so that a uniform principle of action was not realized for the RNA viruses of prokaryotic and eukaryotic host organisms.

Antimicrobial activity of 3-methyl-5-furfurylidene-2-thioxo-4-thiazolidones.

Substituted 3-methyl-5-furfurylidene-2-thioxo-4-thiazolidones 1-17 were tested for their action against Bacillus pumilus, B. brevis and B. megaterium and against Aspergillus flavus, A.

Formazans and tetrazolium salts as potential antibacterial, antifungal, and antiviral agents.

Fifteen 1-aryl-3-(3'-nitro-4'-methoxyphenyl)-5-phenyl formazans and five 3-aryl-5-(3'-nitro-4'-methoxy phenyl)-2-phenyl tetrazolium bromides have been tested against Escherichia coli and Pseudomonas aeruginosa for their antibacterial and against Aspergillus flavus and Helminthosporium gramineum for their antifungal activities. Most of the compounds have shown promising antibacterial and antifungal action. These compounds were also found to exhibit significant antiviral activity against sunnhemp rosette virus in Cyamopsis tetragonoloba plants in vivo as well as in vivo.

The purification and nature of an antiviral protein from Cuscuta reflexa plants.

An antiviral substance, showing highly significant virus inhibiting property, has been isolated from the aqueous extract of Cuscuta reflexa plants. The biologically active virus inhibitor was purified by fractionation with organic solvents followed by precipitation with a saturated solution of ammonium sulphate, dialysis, ultracentrifugation and filtration through a Sephadex G-200 column. It shows characteristics of proteins with a molecular weight around 14,000-18,000 daltons.