Publications by authors named "Awaneesh Kumar"

Article Synopsis
  • The study investigates the outcomes and complications of chronic total occlusion rotational atherectomy (CTO RA) compared to non-CTO RA in patients with coronary artery disease (CAD) through a meta-analysis of existing research.
  • Four studies with 1,868 patients were analyzed, revealing that while CTO RA showed a slight increase in the risk of coronary perforation, the overall risks for major adverse cardiovascular events, target vessel revascularization, and all-cause mortality were not significantly different from non-CTO RA.
  • The findings suggest that more research is needed to understand the implications of CTO RA better and refine treatment approaches, especially given the potential for increased complications.
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Background: The use of rotational atherectomy (RA) in percutaneous coronary intervention (PCI) of acute coronary syndrome (ACS) is considered relatively contraindicated. There have been several observational studies showing RA use in ACS, however, no systemic studies have been undertaken. We sought to evaluate the feasibility and outcomes of RA PCI in ACS by performing a meta-analysis.

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Background: Exercise stress testing is frequently used to expose cardiac arrhythmias. Aerobic exercise conditioning has been used as a nonpharmacologic antiarrhythmic intervention.

Objective: The purpose of this study was to test the hypothesis that noninvasively recorded skin sympathetic nerve activity (SKNA) is increased during exercise and that SKNA response varies according to fitness levels.

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Background: Targeted temperature management (TTM) improves neurologic outcome after cardiac arrest. However, better neurologic prognostication is needed.

Objective: The purpose of this study was to test the hypothesis that noninvasive recording of skin sympathetic nerve activity (SKNA) and its association with heart rate (HR) during TTM may serve as a biomarker of neurologic status.

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Background: Autonomic imbalance is the proposed mechanism of syncope during a tilt table test (TTT). We have recently demonstrated that skin sympathetic nerve activity (SKNA) can be noninvasively recorded using electrocardiographic electrodes.

Objective: The purpose of this study was to test the hypothesis that increased SKNA activation precedes tilt-induced syncope.

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Background: The effects of sedative and anesthetic agents on sympathetic nerve activity (SNA) are poorly understood.

Objective: The purpose of this study was to determine the effects of commonly used sedative and anesthetic agents on SNA in ambulatory dogs and humans.

Methods: We implanted radiotransmitters in 6 dogs to record stellate ganglion nerve activity (SGNA), subcutaneous nerve activity (ScNA), and blood pressure (BP).

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Background: Q waves on a 12-lead ECG are markers of a prior myocardial infarction (MI). However, they may regress or even disappear over time, and there is no specific ECG sign of a non-Q-wave MI. Fragmented QRS complexes (fQRSs), which include various RSR' patterns, without a typical bundle-branch block are markers of altered ventricular depolarization owing to a prior myocardial scar.

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Background: A left ventricular aneurysm (LVA) occurs between 3.5% and 9.4% of all cases of acute myocardial infarction.

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