Publications by authors named "Awa Cisse"
Article Synopsis
- * A study conducted in Senegal analyzed the genetic diversity of PfCyRPA in 95 malaria isolates, finding a mostly common wild type allele, with 15 identified single nucleotide polymorphisms (SNPs), mostly appearing as unique changes.
- * Structure-based modeling showed that while most SNPs have minor effects on PfCyRPA antibodies, some may significantly affect its structure or interaction with the viral protein PfRH5, providing insights for future malaria vaccine design.
Vaccines to the Plasmodium falciparum reticulocyte binding-like protein homologue 5 (PfRH5) target the blood-stage of the parasite life cycle. PfRH5 has the potential to trigger the production of strain-transcendent antibodies and has proven its efficacy both in pre-clinical and early clinical studies. Vaccine-induced monoclonal antibodies (mAbs) to PfRH5 showed promising outcomes against cultured P.
View Article and Find Full Text PDFHepatic genomic assessment of dietary ingestion of 2-aminoanthracene in Sprague Dawley rats.
J Environ Sci Health B
March 2023
This research aims to investigate the effects of 2-aminoanthracene (2-AA), a polycyclic aromatic hydrocarbon (PAH), on the liver. PAH is a by-product of the incomplete combustion of fossil fuels. Specifically, the impact of 2-AA on different body tissues in animals has been reported.
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