Jobelyn suppresses hippocampal neuronal apoptosis and necrosis in experimental alcohol-induced brain stress.

Neurodegeneration in the hippocampus is a consequence of alcohol abuse which compromises the survival of the CNS tissue and its self-renewal capacity. So far, conventional drugs have not been clinically satisfactory in ameliorating neurodegeneration, therefore there has been a surge towards exploring the potentials of nutraceuticals since they mediate their action in a multi-mechanism fashion and may have high therapeutic potentials in CNS diseases. This study, therefore, evaluated the effect of Jobelyn® supplementation in ethanol-induced neurodegeneration of the hippocampus.

Excruciating effect of formaldehyde exposure to students in gross anatomy dissection laboratory.

Background: Formaldehyde is extensively used for preservation of cadavers in departments of anatomy. However, it is a noxious chemical which may cause serious health problems.

Objective: To assess the effect of exposure of medical students to formaldehyde at the Department of Anatomy, Niger Delta University, Nigeria.

Palmar and digital dermatoglyphic patterns in the Ndokwas of Delta State, Nigeria.

We determined asymmetry, complexity and pattern polarization of dermal ridges and palmar variables of atd angle, a - b ridge count and total finger ridge count of dermal ridges among the Ndokwa people of Nigeria. 400 healthy students who are Ndokwas were studied. Ink prints of their fingers and palms were obtained.

Reduction of hippocampal CA 1 neurons in Wistar rats following the administration of phenytoin for seven days.

This study evaluated the neurotoxic effect of parenteral Phenytoin on the Cornu Ammonis 1 (CA 1) region of the Hippocampus in Wistar rats.Twenty wistar rats were randomized into two groups of ten animals each with the experimental group receiving intraperitoneal Phenytoin at a dose of 25 mg/kg body weight per day for seven days while the control group had sham injection of normal saline at equivalent volume for the same period. Hippocampal sections were processed for histology using routine paraffin sectioning followed by Heamatoxylin and Eosin staining.

Curcuma longa extract as a histological dye for collagen fibres and red blood cells.

Crude ethanolic extract and column chromatographic fractions of the Allepey cultivar of Curcuma longa Roxb, commonly called turmeric (tumeric) in commerce, were used as a stain for tissue sections. Staining was carried out under basic, acidic and neutral media conditions. Inorganic and organic dissolution solvents were used.

Collagen and muscle stain obtained from Sorghum bicolor.

Crude ethanolic extracts of the leaves of Sorghum bicolor L. Moench were used as stains for tissue sections. The alkaline mixtures did not stain any of the tissues used but the acidic and neutral alcoholic mixtures stained collagen fibres, muscles and red blood cells in shades of pinkish-yellow.