Computer-aided diagnosis of eyelid skin tumors using machine learning.

Objective: To develop an automated, new framework based on machine learning to diagnose malignant eyelid skin tumors.

Methods: This study used eyelid lesion images from Sheba Medical Center, a large tertiary center in Israel. Before model training, we pretrained our models on the International Skin Imaging Collaboration (ISIC) 2019 dataset consisting of 25,332 images.

[THE CHALLENGE OF DIAGNOSIS AND TREATMENT IN PEDIATRIC RETINAL DETACHMENT].

Retinal detachment is visually impairing in children and adults. The treatment for retinal detachment is challenging, especially in children. There are many etiologies for retinal detachment such as retinal detachment due to retinal tear (rhegmatogenous), tractional retinal detachment and exudative detachment.

Aflibercept monotherapy or bevacizumab first for diabetic macular edema.

Purpose: Clinical outcome and switch patterns with bevacizumab first treatment strategy for patients with newly diagnosed neovascular age-related macular degeneration (nAMD).

Methods: Retrospective observational study of the number of intravitreal injections of bevacizumab and treatment switch in patients who started intravitreal bevacizumab injections between January 1, 2016 and December 30, 2018.

Results: From January 1 2016 to December 31 2018, 608 eyes of 565 patients started intravitreal injections of bevacizumab for a new diagnosis of nAMD.

Survival and characteristics of retinopathy of prematurity in micro-premature infants.

Objective: To describe the risk and nature of retinopathy of prematurity (ROP) in micro-premature infants (≤26 weeks' gestational age [GA]).

Methods: Retrospective analysis of prospectively collected data from infants born at 22-26 weeks' GA over a 5-year period.

Results: A total of 502 infants were identified, of whom 414 survived to discharge (82.

Pre-operative optical coherence tomography findings in macula-off retinal detachments and visual outcome.

Purpose: To evaluate the correlation between foveal changes in the detached retina in macula-off rhegmatogenous retinal detachments (RRD) and visual acuity outcome following repair.

Design: Retrospective, consecutive, observational case series.

Methods: Consecutive patients presenting with macula-off RRD between July 15 and September 15, 2017, underwent SD-OCT imaging and their medical records were reviewed.

Secondary Posterior Chamber Intraocular Lens Fixation Using Flanged Prolene Sutures as an Alternative to an Anterior Chamber Intraocular Lens Implantation.

Purpose: To describe and evaluate the clinical outcomes of the Flanged Prolene Suture intraocular lens fixation (PIF) technique and compare it to anterior chamber IOL (ACIOL) implantation.

Design: A retrospective comparative review.

Methods: A retrospective comparative review of consecutive patients undergoing secondary IOL implantation was performed.

Transient Macular Thinning during the Use of Heavy Silicone Oil, Densiron 68.

Background: To evaluate the effect of short-term tamponade on macular thickness.

Methods: Retrospective case series. Data were collected from charts of patients who received short-term (less than 90 days) .

DENSIRON 68 HEAVY SILICONE OIL AS A SHORT-TERM INTRAOCULAR TAMPONADE FOR MACULA-ON INFERIOR RETINAL DETACHMENTS-A CASE SERIES.

Purpose: To describe our experience using short-term heavy silicone oil (Densiron 68) for macula-on inferior rhegmatogenous retinal detachments with inferior retinal breaks.

Methods: Retrospective, consecutive, observational case series. Data were retrospectively collected from the medical records of patients who underwent pars plana vitrectomy and Densiron 68 endotamponade for macula-on rhegmatogenous retinal detachment repair.

Orbital Magnetic Resonance Imaging Demonstrates Better Contact between the Gas and Anterior Inferior Retina in Side versus Face-Down Position.

Purpose: To demonstrate the relationship between an intraocular gas bubble, the retina, and the residual intraocular fluid in different head positions using orbital magnetic resonance imaging (MRI) in 3 patients who underwent pars plana vitrectomy (PPV) with gas tamponade.

Design: Novel study.

Participants: Patients undergoing PPV with gas-fluid exchange (sulfurhexafluoride [SF] or perfluoropropane [CF]).

Intraoperative Dexamethasone Intravitreal Implant (Ozurdex) in Vitrectomy Surgery for Epiretinal Membrane.

: To study the effectiveness and safety of the intravitreal dexamethasone implant 0.7 mg (Ozurdex®) in vitrectomy surgery for epiretinal membrane.: This is a prospective, multicenter, pilot study.

Hypotensive efficacy of topical brimonidine for intraocular pressure spikes following intravitreal injections of antivascular endothelial growth factor agents: a randomised crossover trial.

Purpose: To determine the effect of topical brimonidine tartrate prophylaxis on intraocular pressure (IOP) spikes following intravitreal injection of antivascular endothelial growth factor (anti-VEGF) agents.

Methods: This is a randomised crossover trial of consecutive non-glaucomatous eyes receiving intravitreal anti-VEGF injections between December 2016 and July 2017. All eyes were randomly assigned to no prophylaxis or topical brimonidine tartrate 0.

The impact of IgG-4-ROD on the diagnosis of orbital tumors: A retrospective analysis.

This study was to determine the prevalence of immunoglobulin G4 (IgG4)-related orbital disease (IgG4-ROD) among patients who have previously undergone biopsy and were diagnosed to have idiopathic orbital inflammatory disease (IOID) or orbital lymphoproliferative disease (OLD), namely, lymphoma and benign reactive lymphoid hyperplasia (BRLH). This is a retrospective cross-sectional study. The charts and slides of all patients who underwent biopsies and were histopathologically diagnosed to have either IOID or OLD were reviewed.

A novel method for quantifying the amount of trabecular meshwork pigment in glaucomatous and nonglaucomatous eyes.

Purpose: To assess the use of a computerized program for evaluating the amount of trabecular meshwork (TM) pigmentation in normal (control), primary open-angle glaucoma (POAG), and pseudoexfoliation glaucoma/pigmentary dispersion glaucoma (PXFG/PDG) patients.

Methods: All included patients were from the Goldschleger Eye Institute glaucoma clinic. After signing an informed consent, each patient's anterior chamber angle was photographed using a single photo-slit under the same conditions.

Interaction of different antidepressants with acute and chronic methadone in mice, and possible clinical implications.

We studied the interaction of a single dose of different antidepressant medications with a single (acute) dose or implanted mini-pump (chronic) methadone administration in mice, using the hotplate assay. For the acute experiment, subthreshold doses of six antidepressant drugs were administered separately with a single dose of methadone. The addition of a subthreshold dose of desipramine or clomipramine to methadone produced significant augmentation of the methadone effect with each drug (p < 0.

Orbital inflammation as a late complication of frontalis silicone elastomer sling operation for congenital ptosis.

Frontalis suspension with the use of a silicone elastomer is one of the preferred procedures for correcting moderate-to-severe ptosis with poor levator function. This procedure involves the attachment of the upper eyelid to the frontalis muscle by a silicone sling. Although this surgery has been performed for many years, information regarding long-term outcomes and complications is relatively limited.