Evaluation of the Toxicity of Human Dental Pulp-Derived Mesenchymal Stem Cells on Animal Models: An Animal Study.

Introduction: Dental pulp remains one of the important sources of mesenchymal stem cells for most preclinical and clinical studies.

Aim And Objectives: To assess the safety after injecting human dental pulp-derived mesenchymal stem cells by intramucosal and intrabony routes in rabbits for clinical application.

Materials And Methods: Animal studies were carried out among 30 New Zealand male white rabbits (3-5 months old), weighing 1.

Esthetic and Palliative Management of Congenitally Missing Anterior Teeth using All Ceramic Fixed Prosthesis: A Clinical Case Report.

Congenitally missing anterior teeth alters the patient's physiognomy and diction in a big way. Maxillary incisor agenesis, prominently the lateral incisor is the most common congenitally missing permanent tooth, in the anterior maxillary region, which is the esthetic zone, representing approximately 20% of all dental anomalies. Treatment planning is inclusive of; smile design, preparation, perception of the patients, and their expectations in relation to esthetics, interdisciplinary alliance that meets the functional, health, and esthetic needs.