Publications by authors named "Avin Maroof"
Objectives: The main purpose of this study was to determine the frequency of COVID-19 vaccine side effects in patients with rheumatic diseases and to examine any potential associations with medications, disease type, or comorbidities.
Methods: A multicentre cross-sectional study from rheumatology units in different hospitals in Iraq was carried out between 8 of August 2021 and 4th of August 2022. Patients were eligible for inclusion if they have a rheumatic disease and have taken one or more doses of any COVID-19 vaccine.
Article Synopsis
- * The study involved 554 patients from 13 Arab countries, validating the Arabic version of the PsAID-12 with strong internal consistency (Cronbach's α = 0.95) and substantial test-retest reliability (ICC 0.90).
- * Key factors linked to higher PsAID-12 scores included disability, depression, widespread pain, and disease activity, highlighting pain and fatigue as critical concerns for patients with psoriatic arthritis.
JAK/STAT signaling pathway plays a significant role in cytokines and growth factors signaling involved in the pathogenesis of rheumatoid arthritis (RA). STAT3 is a major downstream signaling mediator of important pro-inflammatory cytokines involved in Th-17 cell differentiation playing a significant role in regulating Th-17/ Treg balance and the development of autoimmune diseases, especially RA. Studies also have reported the role of the STAT3 pathway in inflammatory and destructive functions of synovial fibroblasts (SFs) in RA.
View Article and Find Full Text PDFObjective: To assess the value of referral strategies for axial spondyloarthritis (axSpA) in patients with suspicious chronic inflammatory low back pain (LBP), to estimate the value of inflammatory back pain (IBP) for referral, and to identify the predictive factors of the final diagnosis of axSpA in Middle Eastern Arab countries.
Methods: The study was multicentric, prospective, and conducted in LBP first-line clinics (rheumatology, internal, family medicine, orthopedic surgery, neurosurgery, and neurology). Consecutive adult patients aged under 45years were included in case of LBP suspicious of inflammatory nature according to the first-line physician.