Publications by authors named "Avin Hafedi"
SARS-CoV-2 is an oral pathogen that infects and replicates in mucosal and salivary epithelial cells, contributing to oral post-acute sequelae COVID-19 (PASC) and other oral and non-oral pathologies. While pre-existing inflammatory oral diseases provides a conducive environment for the virus, acute infection and persistence of SARS-CoV-2 can also results in oral microbiome dysbiosis that further worsens poor oral mucosal health. Indeed, oral PASC includes periodontal diseases, dysgeusia, xerostomia, pharyngitis, oral keratoses, and pulpitis suggesting significant bacterial contributions to SARS-CoV-2 and oral tissue tropism.
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- - The study evaluated oral Lactobacillus species, focusing on their ability to adhere to oral tissues and their antibacterial effects in patients with periodontitis compared to healthy individuals.
- - A total of 354 isolates were analyzed from both groups, revealing different dominant Lactobacillus species: Lacticaseibacillus paracasei and Limosilactobacillus fermentum in periodontitis patients, while Lacticaseibacillus casei and Lactiplantibacillus plantarum were more prevalent in healthy controls.
- - Key findings suggest that Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus fermentum, and Ligilactobacillus saliv