Background: Autologous chondrocyte implantation (ACI) and matrix-induced autologous chondrocyte implantation (MACI) are performed to treat focal chondral defects (FCDs); both are 2-step procedures involving a biopsy, followed by transplantation. There is little published research evaluating ACI/MACI in patients who undergo a biopsy alone.
Purpose: To determine (1) the value of ACI/MACI cartilage biopsies and concomitant procedures in patients with FCDs of the knee and (2) the conversion rate to cartilage transplantation as well as the rate of reoperation.
Purpose: To determine the effect of resident- vs attending-led surgeries on patient outcomes in ophthalmic surgery.
Design: Systematic review and meta-analysis.
Methods: Two independent authors searched PubMed, EMBASE, and Cochrane Library from inception to March 2022.