Publications by authors named "Avi Gupta"

Article Synopsis
  • - The study introduces a new zebrafish model to examine cardiac damage from hypoxia, addressing limitations in existing models that don't account for low oxygen conditions.
  • - Larval zebrafish exposed to severe hypoxia experience rapid loss of mobility and cardiac arrest, with survival rates and heart recovery varying significantly based on age.
  • - Recovery after hypoxia reveals that while heart rate can return to normal within 24 hours, stroke volume and cardiac output remain significantly impaired, indicating lasting damage that may take up to 72 hours to fully recover.
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Cancer is a debilitating disease for which patients often need caretakers to help them live their lives and complete basic activities. This study aims to characterize the burden of the caretaker. A 14-question survey was sent out to randomly selected United States cancer caretakers to analyze the social, emotional, and physical burden of their caretaking.

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Hemocompatibility is a critical consideration when designing cardiovascular devices. Methods of assessing hemocompatibility range from in vitro protein adsorption and static platelet attachment to in vivo implantation. A standard preclinical assessment of biomaterial hemocompatibility is ex vivo quantification of thrombosis in a chronic arteriovenous shunt.

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Catechol adhesives are limited to two-part curing designs. For the first time, a one-pot catechol adhesive is demonstrated with multiple modes of external activation: self-curing, electrocuring, substrate, and two-part curing. Lap shear adhesion (50 kPa) and viscoelastic properties demonstrate that electrocuring is non-inferior to two-part curing methods.

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Background: In patients with peripheral artery disease (PAD), the severity of symptoms correlates poorly with ankle-brachial index (ABI). The aim of this study was to test the hypothesis that limb perfusion assessed using contrast-enhanced ultrasound (CEU) during contractile exercise varies according to functional class in patients with PAD, particularly those with ABIs in the 0.4 to 0.

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