Publications by authors named "Avi Epsztein"
Background: Mild traumatic brain injuries (mTBIs) pose a significant risk, particularly in the elderly population on anticoagulation therapy. The safety of discharging these patients from the emergency department (ED) with a negative initial computed tomography (CT) scan has been debated due to the risk of delayed intracranial hemorrhage (d-ICH).
Objective: To compare outcomes, including d-ICH, between elderly patients on anticoagulation therapy presenting with mTBI who were admitted versus discharged from the ED after an initial negative head CT scan.
Article Synopsis
- Pyroglutamic acid (PGA) levels rise during oxidative stress and may indicate poor outcomes in patients with infections or sepsis.
- A study tracked patients with acute infections, measuring urine PGA and analyzing its link to mortality and organ failure over 30 days.
- Although higher PGA levels initially seemed linked to increased mortality, further analysis indicated that PGA did not predict worse outcomes when considering other factors like heart rate, suggesting a need for larger studies to clarify PGA's role.