Strain specific behavioral and physiological responses to constant light in male CBA/J and CBA/CaJ mice.

Objective: Being visually impaired increases the likelihood of sleep disorders and altered behavior. This study investigated physiological and behavioral differences in two similar mice substrains when exposed to constant light (LL) - CBA/J with retinal degeneration and CBA/CaJ mice (no retinal degeneration).

Material And Methods: Male CBA/J and CBA/CaJ mice were placed into a 12:12 light:dark cycle or constant light (LL).