Predictability of success of endoscopic vesicoureteral reflux treatment utilizing clinical risk factors and intraoperative injection characteristics.

Introduction: The guidelines lack clarity on how to follow the patients after endoscopic treatment for vesicoureteral reflux (VUR). The most discussed question is the need for voiding cystourethrogram (VCUG). Risk-based approaches that consider patient characteristics, disease severity, or factors related to the surgery itself could reduce its use, but a satisfactory predictive model has not yet been established.

Determinants of Problem-Solving Skills of Nursing Students: Solution-Focused Thinking Skills and Emotional Intelligence.

Background: Problem-solving skills are some of the leading strategies for dynamism in the content and quality of nursing care.

Aim: The present study is aimed at determining nursing students' problem-solving, solution-focused thinking, and emotional intelligence levels and investigating the relationship between their problem-solving skills and these variables.

Methods: The study comprised 305 nursing students in Turkey.

Topology surveillance of the lanosterol demethylase CYP51A1 by signal peptide peptidase.

Cleavage of transmembrane segments on target proteins by the aspartyl intramembrane protease signal peptide peptidase (SPP, encoded by HM13) has been linked to immunity, viral infection and protein quality control. How SPP recognizes its various substrates and specifies their fate remains elusive. Here, we identify the lanosterol demethylase CYP51A1 as an SPP substrate and show that SPP-catalysed cleavage triggers CYP51A1 clearance by endoplasmic reticulum-associated degradation (ERAD).

The Effect of Forgiveness and Resilience on Anxiety, Depression and Stress in Nursing Students.

To examine the effects of forgiveness and resilience on anxiety, depression, and stress in nursing students. Cross-sectional correlational study. The convinient sample of the study consisted of 383 nursing students.

The relationship between resilience and solution-oriented thinking in nursing students.

Objective: This study aimed to determine the relationship between resilience and solution-oriented thinking in nursing students.

Background: Although resilience seems to be related with solution-oriented thinking in nursing students, there are only a few studies investigating these two variables in the literature.

Design: This is a cross-sectional survey study.

New Ibuprofen Cystamine Salts With Improved Solubility and Anti-Inflammatory Effect.

Two novel ibuprofen cystamine salts (IBU-CYS 1 and IBU-CYS 2) are synthesized by coupling the anion of ibuprofen with cystamine dihydrochloride in 1 : 1 and 2 : 1 ratio to improve the solubility and bioavailability of ibuprofen. The salts are characterized by H NMR, FT-IR and UV-Vis spectroscopy, differential scanning calorimetry (DSC), thermogravimetry (TGA, DTA) and X-ray diffraction measurements. IBU-CYS 1 and IBU-CYS 2 show higher solubility (6.

The effect of complex formation on the static and frequency-dependent nonlinear optical properties: A combined experimental and theoretical investigation.

A novel mixed ligand Mn(II) complex of 6-Bromopyridine-2-carboxylic acid (6Brpca) and 4,4'-dimethyl-2,2'-dipyridyl has been prepared and structurally characterized using single-crystal X-ray diffraction. The spectroscopic properties were also analyzed by using FT-IR and UV-Vis spectral techniques. The coordination complexes having transition metal ions are known to have promising optical nonlinearity behavior.

Comparison of Explainable Artificial Intelligence Model and Radiologist Review Performances to Detect Breast Cancer in 752 Patients.

Objectives: Breast cancer is a type of cancer caused by the uncontrolled growth of cells in the breast tissue. In a few cases, erroneous diagnosis of breast cancer by specialists and unnecessary biopsies can lead to various negative consequences. In some cases, radiologic examinations or clinical findings may raise the suspicion of breast cancer, but subsequent detailed evaluations may not confirm cancer.

Relationship between academic teaching staff' mental health literacy levels and beliefs toward mental illness.

Objective: The study aimed to determine the relationship between academic teaching staff' mental health literacy levels and beliefs toward mental illness.

Methods: This cross-sectional study was conducted with 357 academic teaching staff working at a state university in Turkey between July 2021 and February 2022.

Results: Significant predictors of academic teaching staff' beliefs toward mental illness were mental health literacy, department, receiving mental health literacy education, seeking psychiatric help before, having a family member with a mental disorder, willingness to work with someone with a mental disorder, experience with a student with a mental disorder in professional life, and thoughts that students with a mental disorder should continue education.

The Relationship Between Psychological Pain, Spiritual Well-Being, and Social Support in Turkish Women Undergoing Therapeutic or Elective Abortion.

This study was conducted to determine the relationship between psychological pain, spiritual well-being, and social support among Turkish women undergoing therapeutic or elective abortion. The cross-sectional study was conducted with 342 women who were hospitalized in the gynecology and obstetrics service of a city hospital between March 2021 and December 2022 in Turkey. The mean psychological pain, spiritual well-being and perceived social support scores of women undergoing therapeutic/elective abortion were 26.

α-glucosidase, docking and density functional theory studies on novel azide metal complexes.

The goal of this study is to synthesize new metal complexes containing -methyl-1-(pyridin-2-yl)methanimine and azide ligands as α-glucosidase inhibitors for Type 2 diabetes. The target complexes () were synthesized by reacting -methyl-1-(pyridin-2-yl)methanimine (L) with sodium azide in the presence of corresponding metal salts. The investigation of target protein interactions, vibrational, electronic and nonlinear optical properties for these complexes was performed by molecular docking and density functional theory studies.

Investigation of Layered Structure Formation in MgB Wires Produced by the Internal Mg Coating Process under Low and High Isostatic Pressures.

Currently, MgB wires made by the powder-in-tube (PIT) method are most often used in the construction and design of superconducting devices. In this work, we investigated the impact of heat treatment under both low and high isostatic pressures on the formation of a layered structure in PIT MgB wires manufactured using the Mg coating method. The microstructure, chemical composition, and density of the obtained superconductive wires were investigated using scanning electron microscopy (SEM) with an energy-dispersive X-ray spectroscopy (EDS) analyzer and optical microscopy with Kameram CMOS software (version 2.

Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase.

Intramembrane proteolysis regulates important processes such as signaling and transcriptional and posttranslational abundance control of proteins with key functions in metabolic pathways. This includes transcriptional control of mevalonate pathway genes, thereby ensuring balanced biosynthesis of cholesterol and other isoprenoids. Our work shows that, at high cholesterol levels, signal peptide peptidase (SPP) cleaves squalene synthase (SQS), an enzyme that defines the branching point for allocation of isoprenoids to the sterol and nonsterol arms of the mevalonate pathway.

Art Therapy as a Nursing Intervention for Individuals With Schizophrenia.

The aim of the current study was to determine the effects of group art therapy on clinical symptoms, alexithymia, and quality of life among people with schizophrenia. This single-blinded, randomized controlled trial was performed with 66 individuals with schizophrenia from a community mental health center in western Turkey between September 2021 and February 2022. Following art therapy, the intervention group had lower severity of positive, negative, and general psycho-pathology symptoms; lower levels of alexithymia; and higher levels of psychological health, social relationships, and total quality of life than the control group; and the difference between groups was statistically significant ( < 0.

Mental Health Problems Among Adolescents With Mild Intellectual Disability and Relation to Sleep Quality and Perceived Social Support: A Comparative Study.

The current cross-sectional study sought to determine the mental health problems of adolescents with mild intellectual disability (ID) and influencing factors. This study, which used a comparison group, was performed with 188 adolescents (91 with mild ID and 97 without ID) between January 2019 and June 2019 in Turkey. Data were collected using a Personal Information Form, the Strengths and Difficulties Questionnaire, Pittsburgh Sleep Quality Index, and Perceived Social Support Scale.

Effect of Personality Traits and Emotion Regulation Strategies on Risky Behaviors in Adolescents.

The current study investigated the effects of personality traits and emotion regulation strategies on high-risk behaviors among adolescents ( = 1,572). This study used a cross-sectional and correlational research design. Multiple linear regression was used for analysis.

Prognostic Value of the Expression of Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR-1) in Chronic Lymphocytic Leukemia.

The transmembrane receptor tyrosine kinase-like orphan receptor 1 (ROR1) has acted on the causation and sustentation of mature B-cell lymphomagenesis for chronic lymphocytic leukemia (CLL) cells. The study attempted to show whether there is a relationship between the level of ROR1 surface expression in CLL cells and disease findings. The level of ROR1 cell surface expression was determined in accordance with the flow cytometric analysis of CLL patients at the first diagnosis time.

The Relationship Between Spiritual Well-Being and Post-Traumatic Growth in Turkish Patients Undergoing Solid Organ Transplantation.

This study was conducted to determine the relationship between spiritual well-being and post-traumatic growth in solid organ transplant patients. This cross-sectional study was conducted with 366 patients who presented to the organ transplantation polyclinic of a university hospital between September 2021 and February 2022 in Turkey. The mean Post-Traumatic Growth Inventory and Spiritual Well-Being Scale scores of solid organ transplant patients were 81.

The effect of visual and/or auditory distraction techniques on children's pain, anxiety and medical fear in invasive procedures: A randomized controlled trial.

Purpose: This study was conducted to determine the effects of visual and/or auditory distraction techniques applied to children aged 7-12 during invasive procedures on pain, anxiety, and medical fear.

Methods: This single-blinded, randomized controlled trial was carried out in the pediatric emergency department of a public hospital between November 2021 and March 2022. In the study, 144 children were assigned to three different intervention groups, in which a kaleidoscope, music, and virtual reality were applied during invasive procedures, and the control group in which the standard invasive procedure was applied, by using the stratified block randomization method.

Sleep quality in patients with non-functioning pituitary adenoma: impact of replacement therapies with an emphasis on the time of hydrocortisone.

Purpose: Sleep disturbances are widespread and associated with pituitary diseases, even those under long-term therapeutic management. The aim of this study was to investigate sleep quality in patients with non-functioning pituitary adenoma (NFPA) and determine the factors that might influence sleep quality, including the detailed features of replacement therapy.

Methods: Eighty-two patients with NFPA and 82 age- and gender-matched control subjects were included.

A Novel Deep Transfer Learning-Based Approach for Automated Pes Planus Diagnosis Using X-ray Image.

Pes planus, colloquially known as flatfoot, is a deformity defined as the collapse, flattening or loss of the medial longitudinal arch of the foot. The first standard radiographic examination for diagnosing pes planus involves lateral and dorsoplantar weight-bearing radiographs. Recently, many artificial intelligence-based computer-aided diagnosis (CAD) systems and models have been developed for the detection of various diseases from radiological images.