Publications by authors named "Avanti P Jakatdar"
Article Synopsis
- β-nitrostyrene compounds like 3,4-methylenedioxy-β-nitrostyrene (MNS) have shown potential in inhibiting tumor growth and inducing cell death, but their effects on osteosarcoma specifically were previously unexplored.
- In experiments with different osteosarcoma cell lines, MNS significantly reduced cell motility by 72-76% and colony formation by 95-100%, while also disrupting existing colonies in a time- and dose-dependent manner.
- MNS affected human osteoblasts similarly, indicating potential therapeutic benefits, while it had little impact on airway epithelial cells, highlighting the specificity of MNS's effects.
