Publications by authors named "Avan A P Sayer"

Article Synopsis
  • Skeletal muscle dysfunction contributes to sarcopenia and frailty, leading to negative health consequences like falls and increased hospital stays; thus, exploring alternatives to exercise, such as metformin, is essential for treatment.
  • The MET-PREVENT trial is a double-blind, placebo-controlled study aiming to assess the effects of metformin on physical performance in older adults with sarcopenia or pre-frailty, involving 80 participants from UK hospitals over 4 months.
  • The trial has received ethical approvals and aims to share results with participants and their healthcare providers to enhance understanding and treatment options.
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Objective: Multinational studies report undernutrition among 39% older inpatients; importantly, malnutrition risk may further increase while in hospital. Contributory factors include insufficient mealtime assistance from time-pressured hospital staff. A pilot study showed trained volunteers could safely improve mealtime care.

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