Publications by authors named "Austin R Hoggarth"
Study Design: Retrospective Study.
Objective: Myxopapillary ependymomas (MPEs) are a unique subgroup of spinal ependymomas originating from the filum terminale's ependymal glia. The 2021 WHO classification reclassified all MPEs as grade 2, recognizing their higher recurrence risk.
Article Synopsis
- Gliomas are the most common type of brain tumors, making up about 80% of malignant primary brain tumors, with high-grade forms having a poor prognosis and a mean survival of only 12-18 months.
- Contrast-enhanced MRI, the standard method for diagnosing gliomas, struggles to differentiate between tumor recurrence and treatment effects, creating difficulties in monitoring the disease.
- Advances in imaging, particularly PET scans and theranostics, are enhancing diagnosis and treatment for recurrent gliomas, potentially improving patient outcomes and quality of life.
Introduction: Grade 3 solitary fibrous tumor, previously known as anaplastic hemangiopericytoma, is a rare and highly malignant intracranial tumor with a limited understanding of its natural history and treatment outcomes.
Methods: We conducted a retrospective analysis using the Surveillance, Epidemiology, and End Results (SEER) database spanning 2000-2019 to evaluate the clinical characteristics and treatment modalities that influence overall survival in this tumor entity. A cohort of 249 patients with intracranial grade 3 solitary fibrous tumors was identified.
Diffuse hemispheric glioma, H3 G34-mutant, is a recently recognized distinct high-grade glioma with a dismal prognosis. In addition to the H3 G34 missense mutation, numerous genetic events have been identified in these malignant tumors, including , , and, rarely, genes. There are only a few reports to date that have identified mutations in diffuse hemispheric glioma, H3 G34-mutant.
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