Long-term effects of cryopreservation on clinically prepared hematopoietic progenitor cell products.

Background Aims: The question of how long hematopoietic progenitor cells (HPCs) destined for clinical applications withstand long-term cryopreservation remains unanswered. To increase our basic understanding about the stability of HPC products over time, this study focused on characterizing long-term effects of cryopreservation on clinically prepared HPC products.

Methods: Cryovials (n = 233) frozen for an average of 6.