Publications by authors named "Austin J Franklin"
Background: Pyogenic spinal infections (PSIs) are a group of uncommon but serious infectious diseases that are characterized by inflammation of the endplate-disc unit. PSIs are considered more prevalent and aggressive among patients with chronic immunocompromised states. Association between PSIs and liver disease has not been systematically analyzed.
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- Primary spinal infections (PSIs) in children are rare and harder to diagnose due to non-specific symptoms, with most cases being managed without surgery.
- A systematic review showed that surgically treated pediatric PSIs often have severe localized pain and neurological issues, leading to a higher rate of treatment failure compared to those managed conservatively.
- The review highlighted that PSIs are mostly caused by infections, particularly affecting the thoracic region, with cervical infections being more severe, and surgery is only recommended for severe cases.