Publications by authors named "Austin D Snyder"
Brain Behav Immun
January 2025
Article Synopsis
- Traumatic brain injury (TBI) is a major cause of injury-related death and disability in the U.S., and managing neuroinflammation early is crucial for treatment.
- Pioglitazone, a drug that may reduce inflammation after TBI, shows potential but also has unknown long-term effects that can worsen brain conditions.
- Research in mice indicates that acute/subacute treatment with pioglitazone leads to negative outcomes, including brain damage and behavior changes, highlighting the need for sex-based considerations and further investigation before clinical use for TBI.
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