Assessment of Serum Vitamin D Levels in Patients with Vitiligo in Jordan: A Case-Control Study.

Background: Low vitamin D serum levels have been associated with many autoimmune disorders and several other skin diseases. Vitiligo is an autoimmune disease characterized by destruction of melanocytes by immune mechanisms. Melanocytes express vitamin D receptors, and their function can be affected by vitamin D status.

Risk of tuberculosis with the use of anti-TNF medications in psoriasis: incidence, screening and management.

Tumor necrosis factor (TNF) plays an important role in containing mycobacterial infections. With the rapidly increasing role of TNF inhibitors in dermatology, tuberculosis (TB) is becoming an important and worrisome concern to dermatologists. This paper aims to provide a comprehensive review on the incidence of TB in patients treated with anti-TNF, the variety of TB screening methods, and management of these cases.

Photoletter to the editor: A new variant of ichthyosis follicularis with alopecia and photophobia (IFAP) syndrome with coexisting psoriasiform lesions and palmoplantar keratoderma. IFAP-PPK syndrome?

IFAP is an acronym for a rare congenital ectodermal disorder characterized by ichthyosis follicularis, alopecia and photophobia. A recessive X-linked mode of inheritance was initially proposed but recent reports in girls suggested genetic heterogeneity of this syndrome. We herein describe a 1-year-old boy with clinical features typical of IFAP syndrome plus psoriasis-like lesions and palmoplantar keratoderma (PPK).