[Aspergillus fumigatus and Candida albicans in cystic fibrosis: clinical significance and specific immune response involving serum immunoglobulins G, A, and M].

Objective: The aim of this study was to analyze the clinical significance of Aspergillus fumigatus and Candida albicans in respiratory secretions from patients with cystic fibrosis and to assess the immune response to these fungi in serum.

Patients And Methods: The study included 66 patients with cystic fibrosis (34 men; mean age, 16.2 years).

Serologic IgE immune responses against Aspergillus fumigatus and Candida albicans in patients with cystic fibrosis.

Objectives: The objectives of this study were to determine the prevalence of Aspergillus fumigatus and Candida albicans in the sputa of patients with cystic fibrosis (CF), to assess serologic IgE responses of these patients to the presence of fungi in the sputum, to evaluate what effect this may have on clinical status, and to determine how the above-mentioned factors relate to allergic bronchopulmonary aspergillosis (ABPA).

Patients: Seventy-six CF patients (40 male and 36 female patients; age, 15.3 plus minus 8.