Publications by authors named "Aurora Luna-De-Alba"
Antibiotics (Basel)
November 2024
Article Synopsis
- The study investigates the effectiveness of various antimicrobial combinations against multidrug-resistant (MDR) and extensive drug-resistant (XDR) strains of a prominent nosocomial pathogen that poses a significant public health threat.
- Researchers assessed the genetic characteristics of 100 isolates, noting high prevalence of drug resistance genes and variations in expression of efflux pumps and porins, indicating complex resistance mechanisms.
- Two promising combinations, levofloxacin-ampicillin/sulbactam and meropenem-colistin, showed synergistic effects in inhibiting bacterial growth, but differing results across testing methods suggest further research is required to optimize treatment strategies.
