Solvent and HEMA Increase Adhesive Toxicity and Cytokine Release from Dental Pulp Cells.

The aim of the present study was to evaluate the effect of the hydroxyethyl-methacrylate (HEMA) concentration and solvent content of dental adhesives on cell viability and cytokine (IL-1b, IL-6, IL-10, TNF-α) release by human dental pulp cells (HDPCs). HDPCs were obtained from fresh extracted human third molars. Experimental adhesives were prepared containing different concentrations of HEMA (0%, 10%, and 20%) with and without solvent (ethanol 10%).

Short-term hyperprolactinemia decreases allergic inflammatory response of the lungs.

Aims: Prolactin is a major immunomodulator. The present study evaluated the effects of short-term hyperprolactinemia induced by domperidone before ovalbumin antigenic challenge on the lung's allergic inflammatory response.

Main Methods: To induce hyperprolactinemia, domperidone was injected in rats at a dose of 5.