Publications by Auria A Tellechea

Publications by authors named "Auria A Tellechea"

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Denaturation and Aggregation of Interferon-τ in Aqueous Solution.

Ryan R Manning Glenn A Wilson Ryan E Holcomb Nathaniel J Zbacnik Auria A Tellechea

Pharm Res

May 2018

Purpose: To evaluate the different degrees of residual structure in the unfolded state of interferon-τ using chemical denaturation as a function of temperature by both urea and guanidinium hydrochloride.

Methods: Asymmetrical flow field-flow fractionation (AF4) using both UV and multi-angle laser light scattering (MALLS). Flow Microscopy.

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