Publications by authors named "Aurelien de Pommereau"

Article Synopsis
  • Heart failure with preserved ejection fraction (HFpEF) is a serious health issue with few effective treatments available, leading to high morbidity and mortality rates.
  • In a study on pigs with HFpEF, researchers tested the impact of cardiosphere-derived cells (CDCs), which have properties that reduce fibrosis and inflammation, on heart function and structure.
  • The administration of CDCs significantly improved left ventricular diastolic function and reduced interstitial fibrosis, even though it did not affect left ventricular hypertrophy or systolic function.
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Venoarterial extracorporeal membrane oxygenation (VA-ECMO) initiation for patients with cardiogenic shock or cardiac arrest is an attractive strategy since it provides a quick restoration of organ perfusion. One major limitation of VA-ECMO is left ventricle (LV) distension which is associated with poor prognosis. To prevent or treat LV distension, LV decompression may be required.

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Background: The resorbable magnesium scaffold (RMS) has demonstrated a good safety profile to treat de novo lesions. Nevertheless, bifurcation lesions involving a side branch (SB) >2.0 mm in diameter were excluded from these studies, and such lesions remain technically challenging due to concerns of scaffold deformation or fracture.

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Aims: Despite similar efficacy and safety profile in pilot studies, bioresorbable polymer drug-eluting stents (BP-DES) could have potential benefit over latest generation durable polymer (DP)-DES by facilitating vessel healing, therefore reducing inflammation and neoatherosclerosis leading to enhanced clinical safety. Therefore, we sought to perform a meta-analysis of randomized clinical trials (RCTs) comparing the safety and efficacy of everolimus-eluting BP-DES (BP-EES) to second-generation DP-DES.

Methods And Results: We conducted a systematic review and meta-analysis to examine the safety and efficacy of BP-EES in patients treated for coronary artery disease.

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