Publications by authors named "Aurelien Mazet"
Article Synopsis
- Motile cilia and flagella are important organelles involved in movement and are made up of a complex structure called the axoneme, which relies on proteins from numerous genes; defects in these genes can lead to primary ciliary dyskinesia (PCD).
- In a study of 196 infertile men with a specific sperm flagella abnormality known as multiple morphological abnormalities of the flagella (MMAF), researchers identified a harmful variant in the GAS8 gene linked to male infertility.
- The study found that the GAS8 variant disrupts the structure and function of the Nexin-Dynein Regulatory Complex (N-DRC), causing misalignment of microtubules in sperm flagella and resulting in
