Publications by authors named "Aurelien Flatres"

Prolonged mechanical ventilation is often associated with either a decrease (known atrophy) or an increase (supposed injury) in diaphragmatic thickness. Shear wave elastography is a noninvasive technique that measures shear modulus, a surrogate of tissue stiffness and mechanical properties. To describe changes in shear modulus (SM) during the ICU stay and the relationship with alterations in muscle thickness.

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Article Synopsis
  • - Recent research links organ dysfunction in sepsis to disrupted metabolism and mitochondrial dysfunction, highlighting the importance of substrate utilization in understanding these conditions.
  • - Sepsis leads to significant metabolic changes, including altered oxygen consumption and impaired oxidation of glucose and lipids, which are associated with negative outcomes for both animals and humans.
  • - Advances in understanding metabolic dysfunctions may inform new diagnostic methods and treatment strategies for sepsis, enabling personalized approaches by identifying specific patient subgroups.
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Background: Muscle weakness following critical illness is the consequence of loss of muscle mass and alteration of muscle quality. It is associated with long-term disability. Ultrasonography is a reliable tool to quantify muscle mass, but studies that evaluate muscle quality at the critically ill bedside are lacking.

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