Publications by authors named "Aurelien Duboin"
Hum Mol Genet
January 2016
Article Synopsis
- - Rett syndrome (RTT) is a rare disorder that causes loss of motor and language skills, as well as cognitive impairment, primarily due to mutations in the MECP2 gene.
- - Research shows that the absence of MECP2 in glial cells negatively affects neurons, but restoring MECP2 in astrocytes in mice improves movement, anxiety, and lifespan.
- - The study found that the drug Epothilone D can restore microtubule transport in astrocytes lacking MECP2 and improve behavior in RTT-affected mice, suggesting potential for innovative treatment.
