Publications by authors named "Aurelie Schirmann"

Context: Erectile dysfunction (ED) is a common sexual disorder. In France, recent evidence-based guidelines are lacking.

Aim: To provide practice guidelines on ED therapeutic management.

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Background: A significant proportion of trans women is demanding for a genital gender-affirming surgery, with vulvo-vaginoplasty being the most frequently requested procedure. The gold standard for primary vaginoplasty in trans women is the penile skin inversion technique with scrotal skin graft, which allows for increased depth of the vaginal cavity.

Aims: The assessment of vulvo-vaginoplasty outcomes utilizing penile skin inversion and scrotal skin graft in individuals assigned male at birth in the surgeon's learning curve involves evaluating aesthetics, functionality, and sexual aspects.

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Article Synopsis
  • Urethral stricture has a prevalence of about 0.9%, and while endoscopic treatments have been the primary approach, their effectiveness has led to a shift towards urethroplasty as the preferred treatment from 2013 to 2022.
  • Data from the Scansanté platform shows that while endoscopic procedures remain common, urethroplasties have increased noticeably since 2019, rising from 1,100 to 1,600 cases from 2020 to 2022.
  • Despite urethrotomies still outnumbering urethroplasties by a large margin, the gap is narrowing, and urethroplasty, particularly with augmentation techniques, is now recognized as
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Article Synopsis
  • - This systematic review aimed to assess the occurrence of genital prolapse in trans women undergoing vulvovaginoplasty, analyzing studies published since 1995 to identify prevalence, risk factors, and treatment options.
  • - The review included 24 studies with over 3,000 patients, showing an overall prolapse rate of 2.7%, with lower rates associated with penile skin inversion techniques compared to intestinal vaginoplasty.
  • - The main risk factor for developing genital prolapse post-surgery was identified as a high body mass index, while surgical prevention techniques often included fixation to the sacrospinous ligament and vaginal packing.
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Introduction: Andrology and urogenital reconstruction are emerging disciplines in French urology. The aim of our study was to evaluate the evolution of andrological surgical procedures over the period 2013-2022 using national data.

Materials And Methods: We collected national common classification of medical acts (CCAM) coding data for all procedures involving andrological surgery from the Scansanté internet platform set up by the Technical Agency for Information on Hospitalisation, which collects prospectively from healthcare structures all procedures coded according to CCAM coding.

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Introduction: With 50 years' experience, inflatable penile implants are the preferred option for erectile dysfunction refractory to pharmacological and mechanical treatment. Technical and surgical improvements have optimized patient success and satisfaction. However, multi-factorial dissatisfaction persists.

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Objective: AI-derived language models are booming, and their place in medicine is undefined. The aim of our study is to compare responses to andrology clinical cases, between chatbots and andrologists, to assess the reliability of these technologies.

Material And Method: We analyzed the responses of 32 experts, 18 residents and three chatbots (ChatGPT v3.

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Article Synopsis
  • The use of artificial intelligence (AI) in the medical field, especially in urology, is growing, enabling quicker access to current scientific knowledge which traditionally took years to master.
  • In a study comparing the performance of AI tools (ChatGPT 3.5, ChatGPT 4.0, and Bard) against 736 human participants on a urological assessment, ChatGPT 4.0 performed the best, scoring 80 points and ranking near the top 10%.
  • Despite showing promising results, the study emphasizes that current AI systems can make mistakes and highlights the need for careful evaluation of their role in medical education and information sharing.
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Platelets are known to enhance the wound-healing activity of mesenchymal stem cells (MSCs). However, the mechanism by which platelets improve the therapeutic potential of MSCs has not been elucidated. Here, we provide evidence that, upon their activation, platelets transfer respiratory-competent mitochondria to MSCs primarily via dynamin-dependent clathrin-mediated endocytosis.

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