Eyelids metastases from uveal melanoma: clinical and histopathologic features of two cases and literature review.

Purpose: To report the clinical and histopathologic features of two cases of eyelids metastases from uveal melanoma diagnosed in a metachronous and synchronous fashion.

Methods: Monocentric retrospective case series of histopathologically proven eyelids metastases from uveal melanoma at our institution.

Results: Two patients were presented to our hospital for upper eyelids pigmented and firm lesions.

Differential profiling of lacrimal cytokines in patients suffering from thyroid-associated orbitopathy.

The aim was to investigate the levels of cytokines and soluble IL-6R in the tears of patients with thyroid-associated orbitopathy (TAO) disease. Schirmer's test was adopted to collect tears from TAO patients (N = 20, 17 women, mean age (±SD): 46.0 years (±13.

Thyroid-Associated Orbitopathy and Biomarkers: Where We Are and What We Can Hope for the Future.

Background: Thyroid-associated orbitopathy (TAO) is the most common autoimmune disease of the orbit. It occurs more often in patients presenting with hyperthyroidism, characteristic of Graves' disease, but may be associated with hypothyroidism or euthyroidism. The diagnosis of TAO is based on clinical orbital features, radiological criteria, and the potential association with thyroid disease.

Thyroid-associated orbitopathy and tears: A proteomics study.

Unlabelled: To date, Thyroid-Associated Orbitopathy (TAO), an autoimmune inflammatory disease affecting the eye, remains poorly characterised and its diagnosis challenging. The aim of this study was to investigate the tears of the TAO patients in order to identify potential biomarkers. Two independent quantitative Tandem Mass Tag™ 6-plex experiments were done.

Ocular adnexal (orbital) solitary fibrous tumor: nuclear STAT6 expression and literature review.

Purpose: To report the clinico-pathological features of solitary fibrous tumor occurring in the ocular adnexa (OA) in a single center. To assess the presence of NAB2-STAT6 genes fusion in OA solitary fibrous tumor detected by nuclear overexpression of STAT6.

Methods: Retrospective study including orbital and OA solitary fibrous tumors treated between 2006 and 2014 in our center.