Publications by authors named "Aurelie Etienne"

Article Synopsis
  • - Reunion Island has seen a resurgence of dengue outbreaks since 2018, with increasing severity and intensity, despite decades of low viral circulation.
  • - A study conducted from 2018 to 2021 showed a rise in severe dengue cases and pediatric infections, with a notable shift in the dominant serotype from DENV2 to DENV1.
  • - The findings suggest dengue is becoming endemic in the region, highlighting the need for health authorities to address the evolving public health implications associated with the disease.
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Background: Anaemia occurs in children when the haemoglobin level in the blood is less than the normal (11 g/dL), the consequence is the decrease of oxygen quantity in the tissues. It is a prevalent public health problem in many low-income countries, including Madagascar, and data on risk factors are lacking. We used existing data collected within the pathophysiology of environmental enteric dysfunction (EED) in Madagascar and the Central African Republic project (AFRIBIOTA project) conducted in underprivileged neighbourhoods of Antananarivo to investigate the factors associated with anaemia in children 24 to 59 months of age.

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Objectives: With a fourth of all under-five children affected, stunting remains one of the biggest health challenges worldwide. Even though the main underlying factors are known, the exact pathways to stunting varying in affected regions, and interventions thus need to be tailored to the local contexts. This study aimed assessing and comparing factors associated with stunting in two understudied sub-Saharan urban contexts with some of the highest stunting prevalence globally: Bangui, Central African Republic (~ 36%) and Antananarivo, Madagascar (42%).

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BackgroundWith more than 300 million infections estimated annually worldwide, dengue is the most prevalent arboviral infection. On Reunion Island, after a large outbreak in 1977-78, only limited episodes of viral circulation or sporadic cases were reported till 2015.AimOur objective was to document and report on the circulation of dengue virus after the occurrence of a small outbreak during austral summer 2015/16 and until the large outbreak of 2018.

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We evaluated awareness of treatment as prevention (TasP) among adults people living with HIV (PLHIV) in five infectious disease departments in Paris, then how they perceived its impact on their sexual well-being. This cross-sectional multicenter survey was conducted in 2014 during scheduled clinical appointments using a self-administered questionnaire. We analyzed 520 questionnaires (42% women, 54% men of whom 57% were MSM [men who have sex with men]).

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Article Synopsis
  • People who inject drugs (PWID) in Georgia, where hepatitis C virus (HCV) prevalence is high, were studied to assess their adherence to treatment and outcomes.
  • An observational study found that 98% of the 244 participants completed their treatment, and 84.8% achieved sustained virologic response (SVR), with adherence being a key factor in success.
  • The study concludes that with peer support and a simple treatment regimen, PWID can achieve good treatment outcomes, showing that concerns about adherence may be overstated.
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Background: Globally one out of four children under 5 years is affected by linear growth delay (stunting). This syndrome has severe long-term sequelae including increased risk of illness and mortality and delayed psychomotor development. Stunting is a syndrome that is linked to poor nutrition and repeated infections.

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Background: Hospitalization is usually recommended for imported malaria. The goal of the present study is to evaluate the evolution in clinical pathways while measuring their impact on mortality.

Methods: This is a 14-year prospective observational study divided into three periods.

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Article Synopsis
  • Ebola virus disease (EVD) is highly fatal, and during the 2014 outbreak, the WHO identified favipiravir as a potential treatment, but ethical concerns prevented randomized trials.
  • Instead, a multicenter non-randomized trial was conducted where all patients received favipiravir to assess its feasibility, safety, and effectiveness in treating EVD.
  • Participants were selected based on specific criteria and received a set dosage of favipiravir, with the goal of gathering preliminary data to inform future research rather than establish definitive treatment guidelines.
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