Publications by authors named "Aurelia Retbi"
Background: Suspected upper gastrointestinal bleeding (SUGIB) is a common issue during ICU stay. In the absence of specific guidelines on the indication and timing of esophagogastroduodenoscopy (EGD), there is substantial variability in EGD indication depending on accessibility and clinical presentation. This study aimed to investigate factors associated with the need for per-EGD hemostatic therapy and to create a score predicting therapeutic benefit of emergency bedside EGD in ICU patients with SUGIB.
View Article and Find Full Text PDFBackground & Aims: There is concern about the burden of liver injury in patients with cancer exposed to immune checkpoints inhibitors (ICIs).
Methods: In a retrospective cohort study, we evaluated the likelihood of grade 3/4 liver injury, of grade 3/4 cholestatic liver injury, and of liver failure, as per the Common Terminology Criteria for Adverse Events (CTCAE) version 5, following treatment with ICIs. We compared these occurrences with a group of cancer patients who were propensity-matched and treated with conventional chemotherapy.
Background: Data are scarce regarding epidemiology and management of critically ill patients with lung abscesses.
Research Question: What are the clinical and microbiological characteristics of critically ill patients with lung abscesses, how are they managed in the ICU, and what are the risk factors of in-ICU mortality?
Study Design And Methods: This was a retrospective observational multicenter study, based on International Classification of Diseases, 10th Revision, codes, between 2015 and 2022 in France. In-ICU mortality-associated factors were determined by multivariate logistic regression.
Article Synopsis
- * Of the 7,485 pediatric COVID-19 cases studied, 26.6% (1,988 patients) were admitted to critical care units, with younger age, pediatric multisystem inflammatory syndrome (PIMS), respiratory issues, and underlying conditions being significant risk factors.
- * The rate of critical care admissions decreased over the pandemic waves, with a total of 32 deaths (0.4%) and a median age of 6 years among those who died, highlighting specific age groups, especially newborn
Background & Aims: There are uncertainties regarding the burden of liver disease in patients with type 2 diabetes (T2D). Thus, we aimed to quantify the burden of liver disease, identify risk factors, and estimate attributable risks in patients with T2D.
Methods: We measured adjusted hazard ratios of liver disease progression to hepatocellular carcinoma and/or decompensated cirrhosis in a 2010-2020 retrospective, bicentric, longitudinal, cohort of 52,066 hospitalized patients with T2D.
This French multicenter retrospective cohort study aimed to describe the autoimmune manifestations (AIMs) associated with lymphoma among patients hospitalized between 2005 and 2016 in three French University Hospitals. Among 2503 patients with lymphoma, 108 (4.3%) had AIMs, mostly autoimmune cytopenias (71.
View Article and Find Full Text PDFLittle is known about the impact of behavioral changes after the 2003 heat wave on hydration status of elderly citizens in France. We used an administrative data file provided information about 23,022 inpatients aged > or =70 years admitted between 2000 and 2006, including vital status at discharge and Charlson comorbidity index and matched it with the result of five blood tests (sodium, potassium, glucose, urea nitrogen, creatinine) within the first 24 h after admission and with daily temperatures before admission. We then measured the prevalence of plasma tonicity (PT) <275 mOsm/l or >300 mOsm/l, blood urea nitrogen/creatinine ratio (BUNC) >100 and inhospital mortality.
View Article and Find Full Text PDFObjective: The objective of the study was to assess and to explain variation of organizational performance in intensive care units (ICUs).
Design: This was a prospective multicenter study.
Setting: The study involved 26 ICUs located in the Paris area, France, participating in a regional database.
Objective: The objective of this study is to develop and validate a questionnaire designed to assess the culture, organization, and management of intensive care units.
Design: This is a prospective multicenter study.
Setting: The study was conducted in 26 intensive care units located in Paris.
Objective: To construct and validate an update of the Simplified Acute Physiology Score II (SAPS II) for the evaluation of clinical performance of Intensive Care Units (ICU).
Design And Setting: Retrospective analysis of prospectively collected multicenter data in 32 ICUs located in the Paris area belonging to the Cub-Rea database and participating in a performance evaluation project.
Patients: 33,471 patients treated between 1999 and 2000.