Mortality related to sickle cell disease and COVID-19 in Brazil, 2020.

Objective: The ability to cause death is the definitive measure of an infectious disease severity, particularly one caused by a novel pathogen like severe acute respiratory syndrome-CoV-2 (COVID-19). This study describes sickle cell disease-related mortality issues during the COVID-19 pandemic in Brazil.

Methods: The provisional 2020 mortality data originated from the public databases of the Mortality Information System and were investigated using the multiple-cause-of-death methodology.

Chronic Obstructive Pulmonary Disease-Related Mortality in Brazil, 2000-2019: A Multiple-Cause-of-Death Study.

Chronic obstructive pulmonary disease (COPD) remains a compelling cause of morbidity and mortality; however, it is underestimated and undertreated in Brazil. Using multiple causes of death data from the Information System on Mortality, we evaluated, from 2000 to 2019, national proportional mortality; trends in mortality rates stratified by age, sex, and macro-region; and causes of death and seasonal variation, considering COPD as an underlying and associated cause of death. COPD occurred in 1,132,968 deaths, corresponding to a proportional mortality of 5.

Cystic fibrosis-related mortality trends in Brazil for the 1999-2017 period: a multiple-cause-of-death study.

Objective: To describe causes of death and mortality data related to cystic fibrosis (CF) using a multiple-cause-of-death methodology.

Methods: Annual mortality data for the 1999-2017 period were extracted from the Brazilian National Ministry of Health Mortality Database. All death certificates in which category E84 (CF) of the ICD-10, was listed as an underlying or associated cause of death were selected.

Trends in abdominal aortic aneurysm-related mortality in Brazil, 2000-2016: a multiple-cause-of-death study.

Objectives: Remarkable changes in the epidemiology of abdominal aortic aneurysm (AAA) have occurred in many countries during last few decades, which have also affected Brazilian mortality concurrently. This study aimed to investigate mortality trends related to AAA mortality in Brazil from 2000 to 2016.

Methods: Annual AAA mortality data was extracted from the public databases of the Mortality Information System, and processed by the Multiple Cause Tabulator.

Sickle cell disease related mortality in Brazil, 2000-2018.

Introduction: There is a demand to update national mortality trends data related to sickle cell disease (SCD) in Brazil. This study describes causes of death and mortality issues related to SCD using the multiple-cause-of-death methodology.

Methods: The annual SCD mortality data was extracted from the public databases of the Mortality Information System by researching deaths in rubric D57 "sickle-cell disorders" of the International Classification of Diseases, Tenth Revision and processed by the Multiple Cause Tabulator.

Causes of death and mortality trends related to hemophilia in Brazil, 1999 to 2016.

Introduction: Multiple cause of death methodology enhances mortality studies beyond the traditional underlying cause of death approach.

Aim: This study aims to describe causes of death and mortality issues related to haemophilia with the use of multiple-cause-of-death methodology.

Methods: Annual male haemophilia mortality data was extracted from the public multiple-cause-of-death databases of the Mortality Information System, searching deaths included in rubrics D66 "hereditary factor VIII deficiency" (haemophilia A), and D67 "hereditary factor IX deficiency" (Haemophilia B) of the International Classification of Diseases, Tenth Revision, and processed by the Multiple Cause Tabulator.

Trends in aortic aneurysm- and dissection-related mortality in the state of São Paulo, Brazil, 1985-2009: multiple-cause-of-death analysis.

Background: Aortic aneurysm and dissection are important causes of death in older people. Ruptured aneurysms show catastrophic fatality rates reaching near 80%. Few population-based mortality studies have been published in the world and none in Brazil.

Mortality profile related to systemic lupus erythematosus: a multiple cause-of-death analysis.

Objective: To analyze the mortality profile related to systemic lupus erythematosus (SLE) in the state of São Paulo, Brazil.

Methods: For the 1985-2007 period, we analyzed all death certificates (n = 4815) on which SLE was listed as an underlying (n = 3133) or non-underlying (n = 1682) cause of death. We evaluated sex, age, and the causes of death, comparing the first and last 5 years of the period, as well as determining the observed/expected death ratio (O/E ratio).

Multiple causes of death related to cerebrovascular diseases in the State of Parana, Brazil.

Objective: To identify associated causes and the number of causes on death certificates that reported cerebrovascular diseases as the underlying cause among residents of the State of Paraná, in Brazil.

Methods: Mortality data in 2004 were obtained on the Datasus website. The population was selected by the TabWin program and multiple causes were processed by the Multiple Causes of Death Tabulator program.

Trends in dermatomyositis- and polymyositis-related mortality in the state of São Paulo, Brazil, 1985-2007: multiple cause-of-death analysis.

Background: Dermatomyositis (DM) and polymyositis (PM) are rare systemic autoimmune rheumatic diseases with high fatality rates. There have been few population-based mortality studies of dermatomyositis and polymyositis in the world, and none have been conducted in Brazil. The objective of the present study was to employ multiple-cause-of-death methodology in the analysis of trends in mortality related to dermatomyositis and polymyositis in the state of São Paulo, Brazil, between 1985 and 2007.

[Chagas disease-related mortality trends, state of São Paulo, Brazil, 1985 to 2006: a study using multiple causes of death].

Objectives: To study mortality trends related to Chagas disease taking into account all mentions of this cause listed on any line or part of the death certificate.

Methods: Mortality data for 1985-2006 were obtained from the multiple cause-of-death database maintained by the São Paulo State Data Analysis System (SEADE). Chagas disease was classified as the underlying cause-of-death or as an associated cause-of-death (non-underlying).

[Paracoccidioidomycosis-related mortality trend, state of São Paulo, Brazil: a study using multiple causes of death].

Objective: To investigate mortality in which paracoccidioidomycosis appears on any line or part of the death certificate.

Method: Mortality data for 1985-2005 were obtained from the multiple cause-of-death database maintained by the São Paulo State Data Analysis System (SEADE). Standardized mortality coefficients were calculated for paracoccidioidomycosis as the underlying cause-of-death and as an associated cause-of-death, as well as for the total number of times paracoccidioidomycosis was mentioned on the death certificates.

[Ill-defined causes of death and unattended deaths, Brazil, 2003].

Background: We studied the distribution of deaths from ill-defined causes that occurred in Brazil during 2003, from which was identified the proportion of unattended deaths.

Methods: Data were obtained from the Mortality Information System, coordinated by the Ministry of Health. Causes of death included in "Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not classified elsewhere" of the International Statistical Classification of Diseases and Related Health Problems, tenth revision, were considered ill-defined, among which the category R98 identified "unattended deaths".

Cysticercosis-related mortality in the State of São Paulo, Brazil, 1985-2004: a study using multiple causes of death.

Cysticercosis-related mortality has not been studied in Brazil. Deaths recorded in the State of São Paulo from 1985 to 2004 in which cysticercosis was mentioned on any line or in any part of the death certificate were studied. Causes of death were processed using the Multiple Cause Tabulator.

[Epidemiological potential of multiple-cause-of-death data listed on death certificates, Brazil, 2003].

Objective: To evaluate the automated processing and the epidemiological potential of multiple-cause-of-death data listed on death certificates in Brazil in 2003.

Methods: Data were obtained from the Brazilian Mortality Information System. The distribution of the number of causes per death certificate was processed using the Multiple Cause of Death Tabulator software and expressed as a percentage of the total deaths in federation units, regions, and in the country as a whole.

[Chickenpox-related mortality trends in the state of São Paulo, Brazil, 1985-2004: a multiple cause approach].

Objective: To study mortality trends related to chickenpox, as either the underlying or associated cause-of-death (recorded in any field of the medical section of the death certificate), in São Paulo, Brazil.

Methods: Mortality data for 1985-2004 were obtained from the multiple cause-of-death database maintained by the São Paulo State Data Analysis System (SEADE). Causes-of-death were processed using the Multiple-Causes-of-Death Tabulator.

[Mycobacterium tuberculosis drug resistance in HIV patients in Baixada Santista, São Paulo, Brazil].

Since the early 1990s, an increase in Mycobacterium tuberculosis drug resistance has been reported, with high prevalence among HIV+ patients. We evaluated the sensitivity patterns of M. tuberculosis, resistance rate, and predisposing factors among HIV+ patients in Santos, São Vicente, Cubatão, Praia Grande, and Guarujá, São Paulo State, Brazil.

Deaths attributed to multiple causes and involving tuberculosis in the state of Rio de Janeiro Brazil between 1999 and 2001.

Objective: To evaluate deaths attributed to multiple causes in which tuberculosis was one of the causes listed.

Methods: All deaths among residents of the state of Rio de Janeiro, Brazil, occurring between 1999 and 2001 and for which the death certificate mentioned tuberculosis, were investigated. The World Health Organization guidelines were used in characterizing the underlying and associated (non-underlying) causes of death.

[Asthma-related mortality, Brazil, 2000: a study using multiple causes of death].

Asthma is underestimated in mortality statistics that only look at the underlying cause of death. We studied deaths of residents in the Brazilian states of Ceará, Pernambuco, Bahia, Minas Gerais, Rio de Janeiro, São Paulo, and Rio Grande do Sul, as well as total deaths in Brazil, where asthma was recorded in any line or part of the death certificate. Causes of death were processed using the Multiple Cause Tabulator.

[Multiple-causes-of-death related to tuberculosis in the State of São Paulo, Brazil, 1998].

Objectives: The goal of this paper is to investigate mortality related to tuberculosis in the state of S o Paulo, southeastern Brazil, according to multiple causes of death and their interrelation with other underlying causes.

Methods: The study investigated deaths related to tuberculosis that occurred in the state of S o Paulo in 1998. Data were obtained from the Fundação Sistema Estadual de Análise de Dados (State System for Data Analysis Foundation - SEADE) database.

[Nosocomial infection and multiple causes of death].

Objective: The purpose of this study was to evaluate the possibility for collecting data on nosocomial infections by means of death certificates.

Methods: The medical charts of children who died after 48 hours of their admission to a pediatric hospital were revised to get information about the causes of death. Death certificates were also revised to verify whether they were properly filled out.