Publications by authors named "Augusto Cama-Olivares"

While renal replacement therapy (RRT) allows for precise fluid management as well as addressing electrolyte imbalances and the removal of other necessary compounds, its early initiation has not shown benefit in the general critically ill population. Moreover, the effects of early RRT initiation specifically in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) also remain unclear. This retrospective study investigated adult patients who underwent VA-ECMO between April 2018 and March 2022 and used the clone-censor-weight method to emulate a hypothetical target trial and compare two groups: patients who initiated RRT within 2 days of VA-ECMO initiation (Early) and those who did not (Late).

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Article Synopsis
  • * A study including 178 adult patients found a high mortality rate of 73%, with factors like a SOFA score of 12 or more indicating a greater risk of death.
  • * Surprisingly, Black patients showed a lower risk of mortality compared to other groups, suggesting that race might play a role in hospital outcomes during severe COVID-19 illness.
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Article Synopsis
  • The study investigates the relationship between different causes of acute kidney injury requiring renal replacement therapy (AKI-RRT) and mortality in hospitalized patients with cirrhosis.
  • Conducted across multiple U.S. hospitals in 2019, the research included 2,063 patients, finding that 18.1% underwent AKI-RRT.
  • Results indicate that while patients with hepatorenal syndrome (HRS-AKI) received different treatment approaches compared to those with other causes of AKI, there was no significant difference in 90-day mortality risk between the two groups.
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Introduction: The FDA authorized the emergency use of enhanced hemoadsorption with oXiris in critically ill adult COVID patients with respiratory failure or severe disease to reduce inflammation. In this study, we evaluated critically ill adult COVID patients with acute kidney injury (AKI) who were exposed versus not exposed to enhanced hemoadsorption with oXiris during continuous renal replacement therapy (CRRT).

Methods: Retrospective cohort study of critically ill adult COVID patients with AKI requiring CRRT.

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Background & Aims: Acute kidney injury (AKI) in cirrhosis is common and associated with high morbidity, but the incidence rates of different etiologies of AKI are not well described in the US. We compared incidence rates, practice patterns, and outcomes across etiologies of AKI in cirrhosis.

Methods: We performed a retrospective cohort study of 11 hospital networks, including consecutive adult patients admitted with AKI and cirrhosis in 2019.

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Introduction: In 2017, the Centers for Medicare and Medicaid Services allowed survivors of hospitalized acute kidney injury requiring dialysis (AKI-D) who were ambulatory and still dependent on hemodialysis (HD) to receive treatment in outpatient dialysis facilities. This policy change generated the ongoing need to improve AKI-D care in the outpatient setting.

Methods: Quality improvement study in adult patients admitted to an outpatient HD unit with the diagnosis of AKI-D.

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