Publications by authors named "Audrey Petit"

Since March 2023, occupational health nurses have been required to have a professional license, a master's degree or an inter-university diploma. They are required to take over 200 hours of theoretical courses, and to complete one or more internships equivalent to over 100 hours.

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Background: Platelet transfusion is considered the standard treatment for preventing or controlling severe haemorrhage in Glanzmann thrombasthenia (GT). However, platelet transfusion can have detrimental effects, including the production of anti-GPIIb/IIIa isoantibodies or anti-HLA antibodies (Ab) and platelet transfusion refractoriness. Recombinant activated factor VII (rFVIIa) has been proposed as an alternative treatment to platelet transfusion.

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A DYNAMIC EXCHANGE? Occupational physicians and general practitioners have different roles but share the common goal of maintaining and promoting the health of the population. Their collaboration is necessary, and both practitioners and employees are generally in favor of it. This collaboration is particularly necessary in several situations: the discovery of a pathology by the occupational physician, the need for temporary incapacity, or difficulties in maintaining employment.

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  • Congenital erythropoietic porphyria (CEP) is a rare genetic disorder resulting from a deficiency in an enzyme crucial for heme biosynthesis, leading to varying severity levels from life-threatening symptoms at birth to milder issues later on.
  • A study reviewed 20 severe perinatal cases of CEP in France, analyzing their presentation and progression through data collected from medical records.
  • Key findings revealed diverse outcomes: some cases involved severe antenatal symptoms like hydrops fetalis and resulted in early mortality, while others showed acute neonatal distress from severe anemia and required hematopoietic stem cell transplantation, which had mixed success rates, highlighting the urgency for improved prenatal and postnatal care strategies.
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  • * A survey involving over 23,000 midwives revealed that while most frequently questioned pregnant women about smoking, only a minority used advanced assessment tools like the Fagerström test.
  • * The findings suggest a need for better training for midwives in smoking cessation strategies, as those who prescribed NRT showed more concern and capability in helping pregnant women quit smoking.
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Background: Low back pain (LBP) is a common musculoskeletal condition and, globally, a leading cause of years lived with disability. It leads to reduced social participation, impaired quality of life, and direct and indirect costs due to work incapacity. A coordinated approach focusing on psychosocial risk factors, active reeducation, and the early use of tools to maintain employment, may be effective for improving prognosis of patients with LBP.

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The overall survival rate after hematopoietic stem cell transplantation (HSCT) for inborn errors of immunity (IEI) has improved considerably, and its indications have broadened. As a consequence, addressing the issue of long-term health-related quality of life (HRQoL) has become crucial. Our study focuses on the health and HRQoL of post-HSCT survivors.

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Pediatric melanoma is a rare cancer, especially in young children, and it remains a diagnostic challenge. We report a case of massively metastatic melanoma in young patient with an atypical clinical and biological presentation and with no risk factors.

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Introduction: Previous international mass-media campaigns for low back pain (LBP) have had conflicting impacts on the general population. The objective was to evaluate the impact of a national back pain campaign conducted between 2017 and 2019 on beliefs and behaviours of general practitioners and the general population in France.

Methods: Between 2017 and 2019, a mass-media campaign was used to disseminate positive messages about LBP using several media, along with a parallel campaign addressed to general practitioners.

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Objective: Cold environments are a potential risk factor for stroke. The aim of this study was to investigate the association between performing work tasks in cold environments and the occurrence of a first stroke event.

Methods: From the French population-based cohort CONSTANCES ('' in French), we collected data from baseline questionnaires along with medical interviews on cardiovascular risk factors and reported exposure to cold temperatures (<10°C) at work.

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  • The transcription factors TWIST1/2 are often overexpressed in cancer, and this study focuses on their roles in neuroblastoma (NB), a childhood cancer with varying outcomes.
  • TWIST1 is linked to worse survival rates and increased metastasis in NB, while TWIST2 is associated with better prognosis.
  • By using CRISPR/Cas9 to suppress TWIST1, researchers found reduced tumor growth and a less aggressive tumor structure, suggesting TWIST1 could be a potential target for new NB therapies.
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Introduction: The self-efficacy to return to work is a major psychological factor of the return to work of patients diagnosed with a cancer. However, french investigations in this field do not take this dimension into account due to the lack of a suitable tool for its assessment. The objective of this study was to provide a french translation and adaptation of the "Return to Work Self-Efficacy' scale - 11 items" (RTWSE-11), validated in dutch language in its original version.

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Purpose: The COVID-19 pandemic and the extended lockdown are associated with numerous changes in behavior and lifestyles. The objective was to assess the impact of the first lockdown on LBP course among chronic LBP patients.

Methods: Descriptive and analytical, cross-sectional, multicenter study, conducted by questionnaire from mid-May to end of June 2020 among patients treated for chronic LBP in 6 French and 1 Swiss center.

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Background: In France, general practitioners (GPs) may use two tools specifically designed to help employees who experience difficulties in returning to work after sick leave: the pre-return-to-work (PRW) medical consultation and therapeutic part-time (TPT) work.

Objectives: The objective was to investigate the level of knowledge and use of these two tools by GPs in Maine-et-Loire, France.

Methods: This cross-sectional study was performed using a telephone questionnaire to evaluate the level of knowledge of GPs and the use of these two tools in patients having difficulties returning to work.

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Background: Indications and techniques of rehabilitation differ widely across types of lumbar surgery, including timing (before or after surgery) and prescriptions (surgeons but also medical or paramedical professionals).

Objectives: This project aimed to build consensual recommendations for practice in this context.

Methods: The SOFMER methodology was used to establish recommendations for physical medicine and rehabilitation: a steering committee defined the types of lumbar surgery involved and developed the main questions to be addressed; a scientific committee performed a literature review for grading evidence and proposed the first version of recommendations, which were discussed during a dedicated session at the national Physical and Rehabilitation Medicine congress; then an e-Delphi method with cross-professional experts was used to finalise recommendations and reach a multidisciplinary consensus.

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Background: Addressing chronic low back pain (cLBP) from the point of view of representation allows better understanding the behaviors associated with it and thus improve its medical and socio-occupational management. The Quebec Questionnaire of Representations related to Work Disability (QRWoD) proposes an evaluation of 9 dimensions of the cLBP-related representation.

Objective: To translate and adapt the QRoWD to French language and assess its validity and reliability in French cLBP workers on prolonged sick leave.

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Objective: To develop guidelines for low back pain management according to previous international guidelines and the updated literature.

Methods: A report was compiled from a review of systematic reviews of guidelines published between 2013 and 2018 and meta-analysis of the management of low back pain published between 2015 and 2018. This report summarized the state-of-the-art scientific knowledge for each predefined area of the guidelines from a critical review of selected literature.

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We have read with great interest the two editorials by Burdorf et al: "The COVID-19 pandemic: one year later - an occupational perspective" (1) and "The COVID-19 (Coronavirus) pandemic: consequences for occupational health" (2). The authors highlight the importance of the societal consequences of the outbreak and changes in the world of work to manage occupational health. The key points identified - such as individual socio-economic factors, psychological effects and occupations with highest risk of contamination - modify return-to-work approaches.

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Purpose: To propose a conceptual framework of the return to work (RTW) of breast cancer survivors (BCS) according to the transactional perspective.

Methods: The Technique for Research of Information by Animation of a Group of Experts was implemented. For each determinant in an initial list established from the literature, experts selected for the consensus exercise were firstly asked to indicate their agreement level individually, via an online questionnaire.

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