Publications by authors named "Audrey Guinot"

Article Synopsis
  • Short Bowel Syndrome (SBS) is a significant cause of intestinal failure in children, and this study evaluates the long-term outcomes of the surgical technique called serial transverse enteroplasty (STEP) used to treat it.
  • The study involved a review of 36 children who underwent STEP between 2000 and 2022, examining their medical histories, surgical details, and nutritional support.
  • Results showed an increase in bowel length and a decrease in dependency on parenteral nutrition, with many children experiencing improved digestive symptoms and growth after the procedure, indicating STEP can be a beneficial option for managing SBS in children.
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Article Synopsis
  • The study looked at whether children with a condition called esophageal achalasia are at a higher risk of a serious problem (esophageal perforation) if they get a procedure called endoscopic dilatation before a different surgery called Heller myotomy.
  • Researchers checked the results from 77 children who had the Heller myotomy between 2000 and 2022, and found that it didn’t matter if they had the dilatation before; the risk of esophageal perforation was the same.
  • They discovered that the only real risk factor for complications after the surgery was if the doctors caused a tear in the esophagus during the procedure.
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Background And Objectives: Patients with Hirschsprung's disease are at risk of developing Hirschsprung-associated enterocolitis, especially in the first 2 years of life. The pathophysiology of this inflammatory disease remains unclear, and intestinal dysbiosis has been proposed in the last decade. The primary objective of this study was to evaluate in a large cohort if Hirschsprung-associated enterocolitis was associated with alterations of fecal bacterial composition compared with HD without enterocolitis in different age groups.

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Introduction: Gastro-esophageal reflux disease (GERD) is the most frequent long-term morbidity of congenital diaphragmatic hernia (CDH) survivors. Performing a preventive fundoplication during CDH repair remains controversial. This study aimed to: (1) Analyze the variability in practices regarding preventive fundoplication; (2) Identify predictive factors for fundoplication.

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Introduction: With advances in surgical and neonatal care, the survival of patients with oesophageal atresia (OA) has improved over time. Whereas a number of OA-related conditions (delayed primary anastomosis, anastomotic stricture and oesophageal dysmotility) may have an impact on feeding development and although children with OA experience several oral aversive events, paediatric feeding disorders (PFD) remain poorly described in this population. The primary aim of our study was to describe PFD in children born with OA, using a standardised scale.

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Airway surgery involving trachea or main stem bronchi in neonates and children is challenging. The use of extracorporeal support for such unusual indications is poorly described. Here, we report on three patients receiving peripheral extracorporeal membrane oxygenation (ECMO) to maintain adequate ventilation while improving surgical site exposure.

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Article Synopsis
  • The study aimed to identify factors influencing the need for antireflux surgery in infants with esophageal atresia during their first year of life.
  • From a total of 835 infants in a French registry, 682 were evaluated; 53 (7.8%) underwent surgery, with various predictors identified, such as anastomotic tension and low birth weight.
  • Key findings suggest that complications like gastroesophageal reflux, poor nutrition, and surgical difficulties significantly increase the likelihood of requiring antireflux surgery in these patients.
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Background: Hirschsprung disease is a rare congenital disease typically requiring surgical treatment during childhood. Quality of life and social condition at adult age can be impaired by disease-specific sequelae.

Objective: This study aimed to assess the quality of life and social outcome of adult patients operated on for Hirschsprung disease during childhood.

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