Publications by authors named "Audrey Gassman"
Article Synopsis
- Black cohosh extract is marketed as a dietary supplement to help relieve menopause symptoms and may protect against bone loss in postmenopausal women; however, its interactions with bisphosphonates like risedronate are unclear.
- A study on female rats examined the effects of black cohosh, risedronate, and their combination on bone mineral density over 24 weeks after ovariectomy.
- Results showed that while high doses of risedronate significantly increased bone mineral density, black cohosh extract had no significant effects alone or in combination with risedronate.
Background: Most breastfeeding individuals take at least one prescription drug, yet limited data from lactation studies are available to inform the safety of these drugs during breastfeeding. As a result, healthcare providers (HCPs) rely on available information about safety of drugs used during pregnancy or on personal experiences to inform prescribing/counseling decisions for breastfeeding individuals. To improve risk communication regarding drugs used during lactation, the U.
View Article and Find Full Text PDFAnticancer agents can impair ovarian function, resulting in premature menopause and associated long-term health effects. Ovarian toxicity is not usually adequately assessed in trials of anticancer agents, leaving an important information gap for patients facing therapy choices. This American Society of Clinical Oncology (ASCO) statement provides information about the incorporation of ovarian toxicity measures in trial design.
View Article and Find Full Text PDFIntroduction: There have been reports of clinically relevant uterine bleeding events among women of reproductive age exposed to rivaroxaban.
Objective: The aim of this study was to compare the risk of severe abnormal uterine bleeding (SAUB) resulting in transfusion or surgical intervention among women on rivaroxaban versus apixaban, dabigatran and warfarin.
Methods: We conducted a retrospective cohort study in the FDA's Sentinel System (10/2010-09/2015) among females aged 18+ years with venous thromboembolism (VTE), or atrial flutter/fibrillation (AF) who newly initiated a direct oral anticoagulant (DOAC; rivaroxaban, apixaban, dabigatran) or warfarin.
Commentary: Guideline for male testosterone therapy: a regulatory perspective.
J Clin Endocrinol Metab
February 2007