Publications by authors named "Audrey Bestion"

Article Synopsis
  • - The study compared mortality rates and patient burden among adult ICU patients with respiratory failure due to RSV, COVID-19, seasonal influenza, and H1N1, involving a total of 807 patients.
  • - Patients with RSV had more comorbidities, while those with COVID-19 presented with less severe conditions at admission, indicated by lower SAPS-II and SOFA scores.
  • - Results showed that COVID-19 and H1N1 were linked to higher mortality rates compared to RSV, despite patients with RSV being more severely ill, suggesting a better overall outcome for those affected by RSV and seasonal influenza.
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Article Synopsis
  • A multicenter study examined the impact of the COVID-19 pandemic on antifungal use in hospitals, noting a potential overuse similar to the trend seen with antibacterials.
  • The study found a significant increase in the consumption of antifungals like voriconazole and caspofungin during 2020 compared to 2019, correlating with higher rates of invasive fungal diseases in both COVID-19 and non-COVID-19 patients.
  • The findings highlight the need for effective antifungal stewardship strategies to manage and control antifungal consumption amidst rising fungal infections during the pandemic.
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Patients with systemic rheumatic disease (SRD) share the risks of multi-organ flare-up, cardiovascular diseases, and immunosuppression. Such situations can lead to an acute critical illness. The present study describes the clinical features of SRD patients admitted to the intensive care unit (ICU) and their short- and long- term mortality.

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Background: Patients with neuromuscular disorders (NMD) share the risk of acute respiratory failure (ARF) leading to ICU admissions. Noninvasive ventilation (NIV) is often proposed as an alternative to invasive ventilation. This study describes clinical features, ventilation management, and outcomes of subjects with NMD admitted to ICU and managed for ARF.

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Patients with thrombophilia and/or a history of venous thromboembolism (VTE) exhibit a high risk of thrombosis during pregnancy. The present multicentre study prospectively assessed a prophylaxis strategy, based on a risk score, in pregnancies with increased risk of VTE. Among 286 patients included in the study, 183 had a personal history of VTE (63.

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