Hepatic lesions of vascular origin in multicentric Castleman's disease, plasma cell type: report of one case with peliosis hepatis and another with perisinusoidal fibrosis and nodular regenerative hyperplasia.

We report two cases of multicentric Castleman's disease, plasma cell type, associated with three different liver lesions. Peliosis hepatis was observed in one case and perisinusoidal fibrosis with nodular regenerative hyperplasia in the other. These observations give some evidence that Castleman's disease, per se, may be involved in these three presumably interrelated liver vascular lesions.

Human hydatidosis in Niger.

Thirty-two cases of hydatidosis were collected in two Nigerian hospitals during a 5-year period; 81% of these had extra-hepatic localizations. Human hydatidosis has been considered as exceptional in West Africa but seems to be an underestimated disease in Niger. Studies in slaughtered animals from Niger show a high prevalence of hydatidosis in camels while no infection was found among sheep.

[Neurologic diseases in Niger].

The authors report the results of a study realized at National Hospital of Niamey (Republic of Niger) from october 1981 to may 1986. Among 4820 patients living in Western Niger, 410 (8.5%) had neurological disorders.

Mycetoma in the Republic of Niger: clinical features and epidemiology.

Mycetoma is a common disease in the Republic of Niger. In two hospitals 133 cases were observed. The major site of lesions was the foot.

[Hydatid cyst of the thyroid. Apropos of a case in the Republic of Niger].

Thyroid echinococcosis has been rarely found, especially in areas where hydatic cysts are rarely encountered. The authors report on a case of thyroid echinococcosis in a patient living in sahelian Africa (Niger), which is classically known as a region of low endemia for hydatic disease.

[A case of hydatid cyst of the mediastinum in the Republic of Niger].

The authors report on an observation made at the Niamey hospital, because of the combined infrequency of both human hydatidosis in western Africa and mediastinal localization of the observed cases.

[Surgical therapy in African mycetoma. Indications a propos of 160 cases].

The authors treated 160 cases of African mycetoma in Mauritania and then in Niger from september 1978 to june 1985. They here underline some guidance in the application of the utilizable surgical techniques, according to environment. The localizations met are described as well as criteria of diagnosis, pathological aspects, and responsible agents.

[63 cases of mycetoma in the Niger Republic (etiological study based on histopathology)].

63 samples of mycetomas were examined between 1981 and 1984. Most of them (53 cases) were actinomycotic mycetomas of which 20 were due to Streptomyces somaliensis, 17 to Actinomadura pelletieri, 11 to Nocardia sp., 4 to Actinomadura madurae.

[Relations of sinusitis and primary glomerulonephritis].

Certain types of glomerulonephritis develop typically as the result of focal infection, and may recover following effective treatment of the infective focus at cause. Apart from the classical immunity mechanism consisting of the formation of immune complexes with the bacterial antigen, a major role for environmental allergens must also be evoked, as well as the probable existence of different immunity mechanisms at the origin of certain types of GN (mainly mesangial GN with IgA deposits and lipoid nephrosis). Invasion of the pulmonary allergen through a rhinosinusal route is responsible for a rhinosinusitis demonstrating a typical clinical features and course.

[Pseudo-lymphomas of the ocular adnexa: their relations to Sjögren's syndrome (author's transl)].

Studies over the last fifteen years, of histological, immunological and hematological parameters has, led to the description of a non-malignant lymphoproliferation: a pseudo-lymphoma which is in the middle of the spectrum between glandular localisation of Sjögren's syndrome and frank neoplasia. This type of proliferation has been also observed in the conjunctiva, without antecedents of Sjögren syndrome. Histologically and immunologically, it is dysimmunitary process which has the potential to regress with appropriate immunosuppressive therapy, or to progress to malignant lymphoma.

[Unusual aspects of Burkitt's disease in Mauritania].

The authors report on four observations on Burkitt's lymphoma fro Mauritania: three nodes lymphoma and one abdomen tumor. Mauritania climatic conditions are far from climatic conditions suitable to Burkitt's lymphoma development. Classical monochemotherapy (cyclophosphamide or methotrexate) were inefficient.

[Various etiologies of systolic murmurs radiating from the apex of the heart to the neck].

The authors studied systolic murmurs in 89 cases, 50 of aortic stenosis, 14 cases of obstructive cardiomyopathy and 20 cases of mitral incompetence. This systolic murmur is characterised by its exceptional intensity, its raspy character at the base, becoming softer at the apex and in the axilla, the presence of a thrill and irradiation into the neck in 50 to 75% of cases. The etiological diagnosis was ensured precisely by 1) pharmaco-dynamic tests: amyl nitrite accentuates the systolic ejection murmurs and attenuates murmurs due to mitral regurgitation.

[Functional aortic systolic murmurs in the elderly].

The authors report a clinical and phonocardiographic study of functional aortic systolic murmurs in 26 elderly patients, in 19 of which the lesion was confirmed pathologically. Systolic murmurs radiating across the chest in elderly have the same clinical characteristics as aortic stenosis from which they may, however, be distinguished owing to the: absence of a thrill during systole. The brief duration and the proto-meso-systolic position of the murmur with early inscription of maximal oscillations on the phonocardiogram.