Publications by authors named "Aude Sirven"

Purpose: To systematically review qualitative studies on outcomes, needs, experiences, preferences, concerns and health-related quality of life (HRQoL) of people surviving cancer in Europe in the last decade.

Methods: Protocol registered ( https://www.crd.

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Background: Patient and public involvement (PPI) has become an essential part of health research. There is a need for genuine involvement in order to ensure that research is relevant to patients. This can then improve the quality, relevance, and impact of health research, while at the same time reducing wasted research and in doing so bringing science and society closer together.

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Background: Elevated body mass index (BMI) represents a risk factor for cancer-related fatigue (CRF). Weight loss interventions are feasible and safe in cancer survivors, leading to improved cardio-metabolic and quality of life (QOL) outcomes and modulating inflammatory biomarkers. Randomized data are lacking showing that a lifestyle intervention aimed at weight loss, combining improved diet, exercise, and motivational counseling, reduces CRF.

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Article Synopsis
  • The study investigates the role of the intestinal microbiome in early breast cancer prognosis using shotgun metagenomics on fecal samples from patients before and after chemotherapy.
  • It finds that certain gut bacteria that are more abundant in breast cancer patients may negatively affect prognosis and are influenced by chemotherapy, potentially worsening side effects like weight gain and neurological issues.
  • The research emphasizes the need for further validation of these findings in larger prospective studies to confirm the gut microbiome's impact on breast cancer treatment outcomes.
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