Publications by authors named "Aude Manetti"

Objectives: Despite evidence of low representativeness of clinical trial results for depression in adults, the generalizability of clinical trial results for late-life depression is unknown. This study sought to quantify the representativeness of pharmacologic and psychotherapy clinical trial results for late-life unipolar depression.

Method: Data were derived from the 2004-2005 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally representative sample of 34,653 adults from the United States population.

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Objectives: This study sought to determine the clinical and sociodemographic correlates and the treatment-seeking rate of major depressive disorder (MDD), diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, among older adults and its association with comorbid psychiatric disorders and perceived health status.

Methods: Data were drawn from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions, a large cross-sectional survey (N = 43,093) representative of the US population.

Results: Compared with participants aged 65 years and older without a 12-month diagnosis of MDD, those with MDD were more likely to have lifetime and 12-month comorbid psychiatric disorders.

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Article Synopsis
  • The aging population is increasing due to longer life expectancy, creating a greater demand for healthcare services tailored to their needs, especially regarding mental health issues like depression.
  • About 20% of elderly residents in public facilities suffer from major depressive episodes, leading to higher risks of suicide and reduced quality of life.
  • There is a need to improve physicians' skills in recognizing and treating depression in older adults, as well as to create specialized psychiatric wards in hospitals and nursing homes to better support this vulnerable group.
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  • - The study aimed to investigate the prevalence and impact of personality disorders among adults aged 65 and older, including their sociodemographic factors and comorbid conditions.
  • - Data from the National Epidemiologic Survey revealed that 8.07% of older adults had at least one personality disorder, with obsessive-compulsive personality disorder being the most common, and these individuals experienced a lower quality of life.
  • - The research highlights a strong link between personality disorders and various disabilities and medical/psychiatric issues in older adults, suggesting a need for improved prevention and intervention strategies for this age group.
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  • * Using data from a large national survey, the researchers compared the rates of pure MDD and MDD plus subthreshold hypomania across different age groups.
  • * The results indicate that older adults have significantly lower prevalence of subthreshold hypomania, while their rates of pure MDD are similar to those of younger adults, suggesting that medical conditions may also play a role in older individuals experiencing depression.
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Background: Post-traumatic stress disorder (PTSD) is a severe anxiety disorder whose symptoms include re-experiencing, avoidance, and hyperarousal after a particularly intense event. In view of the aging of the population, increased clinical knowledge is required for better understanding of PTSD in the elderly. Extending previous research in this field in adults and children, the aim of our study was to assess the utility of peri-traumatic dissociation and distress as a predictor of PTSD in the elderly.

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