Publications by authors named "Atzin S Ruiz-Hernandez"
Article Synopsis
- Pulse-wave velocity (PWV), flow-mediated dilation (FMD), and carotid intima-media thickness (CIMT) are key methods for assessing arterial health and identifying cardiovascular issues, especially in populations with various risk factors like diabetes and hypertension.
- These tests help in the early detection of vascular diseases and assist in treatment decisions, ultimately improving patient outcomes.
- Recent studies highlight the need to include these assessments in evaluating cardiovascular health for patients with obesity and metabolic syndrome, allowing for better risk stratification and management.
Article Synopsis
- Critical limb ischemia is a severe form of peripheral arterial disease, and while angioplasty can improve blood flow, some patients still face the risk of limb amputation.
- This study focused on 20 patients undergoing angioplasty to monitor the behavior of endothelial progenitor cells (EPCs) and their potential to predict outcomes in terms of limb amputation.
- Findings indicated that a higher number of certain EPC subpopulations before the procedure and reduced reactivity afterward were associated with an increased risk of major limb amputation within a 30-day follow-up.
Enlarged adipocytes from subcutaneous vs. visceral adipose tissue differentially contribute to metabolic dysfunction and atherogenic risk of patients with obesity.
Sci Rep
January 2021
Morphological characteristics and source of adipose tissue as well as adipokines may increase cardiometabolic risk. This study aimed to explore whether adipose tissue characteristics may impact metabolic and atherogenic risks. Subcutaneous Adipose Tissue (SAT), Visceral Adipose Tissue (VAT) and peripheral blood were obtained from obese patients submitted to bariatric surgery.
View Article and Find Full Text PDFCritical limb ischemia (CLI) represents an advanced stage of the peripheral arterial disease. Angioplasty improves the blood flow to the lower limb; however, some patients irreversibly progress to limb amputation. The extent of vascular damage and the mechanisms of vascular repair are factors affecting post-angioplasty outcome.
View Article and Find Full Text PDFMajor adverse cardiovascular events (MACEs) negatively impact the cardiovascular prognosis of patients undergoing coronary angioplasty due to coronary ischemic injury. The extent of coronary damage and the mechanisms of vascular repair are factors influencing the future development of MACEs. Intrinsic vascular features like the plaque characteristics and coronary artery complexity have demonstrated prognostic information for MACEs.
View Article and Find Full Text PDFUnlabelled: Currently, there are no confident prognostic markers in patients with coronary artery disease (CAD) undergoing angioplasty. The present study aimed to explore whether basal coronary circulating Mononuclear Progenitor Cells (MPCs) and vascular injury biomarkers were related to development of major adverse cardiovascular events (MACEs) and may impact clinical prognosis.
Methods: The number of MPCs and soluble mediators such as IL-1β, sICAM-1, MMP-9, malondialdehyde, superoxide dismutase and nitric oxide were determined in coronary and peripheral circulation.
Neutrophil-to-lymphocyte ratio and its relation with pro-inflammatory mediators, visceral adiposity and carotid intima-media thickness in population with obesity.
Eur J Clin Invest
May 2019
Background: Atherosclerosis represents a cardiovascular risk. Chronic inflammation is a key factor for atherogenic progression. Neutrophil-to-lymphocyte ratio (NLR) has been proposed as a novel biomarker for cardiovascular risks.
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