Incidental detection of FGFR3 fusion via liquid biopsy leading to earlier diagnosis of urothelial carcinoma.

The rising utilization of circulating tumor DNA (ctDNA) assays in Precision Oncology may incidentally detect genetic material from secondary sources. It is important that such findings are recognized and properly leveraged for both diagnosis and monitoring of response to treatment. Here, we report a patient in whom serial cell-free DNA (cfDNA) monitoring for his known prostate adenocarcinoma uncovered the emergence of an unexpected FGFR3-TACC3 gene fusion, a BRCA1 frameshift mutation, and other molecular abnormalities.

Interventions promoting colorectal cancer screening in the Hispanic population: a review of the literature.

Purpose: To review the literature on the interventions used in the promotion of colorectal cancer (CRC) screening in the Hispanic population.

Organizing Construct: CRC screening and Hispanic Americans.

Methods: Literature published between 1999 and 2010 was reviewed using PubMed, Cumulative Index to Nursing and Allied Health Literature Plus, and Cochrane Library using the key words colorectal cancer, colorectal cancer screening, and Hispanic Americans.